Antiulcer Activity of Extracts of Ecdysteroid-Containing Plants of Genera Lychnis and Silene of the Caryophyllaceae Family

被引:0
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作者
S. G. Krylova
E. P. Zueva
L. N. Zibareva
E. N. Amosova
T. G. Razina
机构
[1] Siberian Division of the Russian Academy of Medical Sciences,E. D. Goldberg Research Institute of Pharmacology
[2] National Research Tomsk State University,undefined
关键词
Lychnis and Silene extracts; antiulcer activity; ecdysteroids;
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摘要
We studied antiulcer activity of the extracts of ecdysteroid-containing plants of the Caryophyllaceae family: Lychnis chalcedonica L., Silene viridiflora L.Sp.Pl., and Silene frivaldszkyana Hampe. Experiments on the model of neurogenic and aspirin-induced ulcerogenesis showed unidirectional and pronounced gastroprotective effects of S. viridiflora and L. chalcedonica extracts comparable to the efficacy of famotidine. In these models, a course of intragastric treatment with the extracts reduced ulcerative lesions of all types.
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页码:225 / 228
页数:3
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