Antiulcer Activity of Extracts of Ecdysteroid-Containing Plants of Genera Lychnis and Silene of the Caryophyllaceae Family

被引：0
|
作者：
S. G. Krylova
E. P. Zueva
L. N. Zibareva
E. N. Amosova
T. G. Razina
机构：
[1] Siberian Division of the Russian Academy of Medical Sciences,E. D. Goldberg Research Institute of Pharmacology
[2] National Research Tomsk State University,undefined
来源：
Bulletin of Experimental Biology and Medicine | 2014年 / 158卷
关键词：
Lychnis and Silene extracts; antiulcer activity; ecdysteroids;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We studied antiulcer activity of the extracts of ecdysteroid-containing plants of the Caryophyllaceae family: Lychnis chalcedonica L., Silene viridiflora L.Sp.Pl., and Silene frivaldszkyana Hampe. Experiments on the model of neurogenic and aspirin-induced ulcerogenesis showed unidirectional and pronounced gastroprotective effects of S. viridiflora and L. chalcedonica extracts comparable to the efficacy of famotidine. In these models, a course of intragastric treatment with the extracts reduced ulcerative lesions of all types.
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页码：225 / 228
页数：3
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