Roles of Sphingosine-1-Phosphate in Reproduction

被引：1
|
作者：
Lei Guo
Xianghong Ou
Hong Li
Zhiming Han
机构：
[1] Southern Medical University,Department of Obstetrics and Gynecology, Center for Reproductive Medicine, Nanfang Hospital
[2] Chinese Academy of Sciences,State Key Laboratory of Reproductive Biology, Institute of Zoology
来源：
Reproductive Sciences | 2014年 / 21卷
关键词：
sphingosine-1-phosphate; ovary; germ cell; oocyte; preimplantation embryo;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Sphingosine-1-phosphate (S1P) plays crucial roles in the regulation of cell growth, proliferation, differentiation, cell survival, migration, and angiogenesis. In the reproductive system, S1P protects mammalian germ cells from irradiation or chemotherapy-induced cell death in vivo and in vitro. Moreover, S1P could improve the survival rate of thawed ovary and transplanted ovary. Furthermore, S1P could improve the developmental potential of oocyte and preimplantation embryo. In conclusion, S1P plays important roles in reproduction.
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页码：550 / 554
页数：4
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