Roles of Sphingosine-1-Phosphate in Reproduction

被引：1
|
作者：
Lei Guo
Xianghong Ou
Hong Li
Zhiming Han
机构：
[1] Southern Medical University,Department of Obstetrics and Gynecology, Center for Reproductive Medicine, Nanfang Hospital
[2] Chinese Academy of Sciences,State Key Laboratory of Reproductive Biology, Institute of Zoology
来源：
Reproductive Sciences | 2014年 / 21卷
关键词：
sphingosine-1-phosphate; ovary; germ cell; oocyte; preimplantation embryo;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Sphingosine-1-phosphate (S1P) plays crucial roles in the regulation of cell growth, proliferation, differentiation, cell survival, migration, and angiogenesis. In the reproductive system, S1P protects mammalian germ cells from irradiation or chemotherapy-induced cell death in vivo and in vitro. Moreover, S1P could improve the survival rate of thawed ovary and transplanted ovary. Furthermore, S1P could improve the developmental potential of oocyte and preimplantation embryo. In conclusion, S1P plays important roles in reproduction.
引用
下载
收藏
页码：550 / 554
页数：4
相关论文
共 50 条
  • [21] Role for sphingosine kinase and sphingosine-1-phosphate in inflammation
    Crellin, H
    El Alwani, M
    Kawamori, T
    Obeid, L
    PROSTAGLANDINS & OTHER LIPID MEDIATORS, 2006, 79 (1-2) : 145 - 145
  • [22] Sphingosine-1-phosphate and melanocyte survival
    Park, K
    Kim, D
    Choi, H
    Kim, S
    Kwon, S
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2005, 124 (04) : A130 - A130
  • [23] Sphingosine-1-phosphate and renal vasoconstriction
    Jensen, B. L.
    ACTA PHYSIOLOGICA, 2018, 222 (02)
  • [24] Sphingosine-1-phosphate receptor 2
    Adada, Mohamad
    Canals, Daniel
    Hannun, Yusuf A.
    Obeid, Lina M.
    FEBS JOURNAL, 2013, 280 (24) : 6354 - 6366
  • [25] Sphingosine-1-phosphate signaling and the skin
    Herzinger, Thomas
    Kleuser, Burkhard
    Schaefer-Korting, Monika
    Korting, Hans Christian
    AMERICAN JOURNAL OF CLINICAL DERMATOLOGY, 2007, 8 (06) : 329 - 336
  • [26] Understanding sphingosine-1-phosphate transport
    Sarah Crunkhorn
    Nature Reviews Drug Discovery, 2023, 22 : 538 - 538
  • [27] Endothelial Functions of Sphingosine-1-phosphate
    Lucke, Susann
    Levkau, Bodo
    CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2010, 26 (01) : 87 - 96
  • [28] SPHINGOSINE-1-PHOSPHATE LYASE INHIBITORS
    BOUMENDJEL, A
    MILLER, SPF
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1994, 207 : 259 - ORGN
  • [29] Paradoxical effects of sphingosine-1-phosphate
    Bollag, WB
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2003, 120 (04) : XIII - XIV
  • [30] AN EFFICIENT SYNTHESIS OF SPHINGOSINE-1-PHOSPHATE
    KRATZER, B
    SCHMIDT, RR
    TETRAHEDRON LETTERS, 1993, 34 (11) : 1761 - 1764
12345