Multi-omics on our multitudes

被引：0
|
作者：
Richard A. Voit
Vijay G. Sankaran
机构：
[1] Harvard Medical School,Division of Hematology/Oncology, Boston Children’s Hospital and Department of Pediatric Oncology, Dana
[2] Broad Institute of MIT and Harvard,Farber Cancer Institute
来源：
Nature Genetics | 2022年 / 54卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Clonal expansion of DNMT3A-mutant hematopoietic stem cells is a risk factor for myeloid malignancies and other morbidities. A new study uses multi-modal single-cell genomics to characterize the myeloid differentiation bias of DNMT3A-mutated clones, and finds preferential hypomethylation of binding motifs for key transcriptional regulators.
引用
下载
收藏
页码：1449 / 1450
页数：1
相关论文
共 50 条
  • [1] Multi-omics on our multitudes
    Voit, Richard A.
    Sankaran, Vijay G.
    NATURE GENETICS, 2022, 54 (10) : 1449 - 1450
  • [2] Survey on Multi-omics, and Multi-omics Data Analysis, Integration and Application
    Shahrajabian, Mohamad Hesam
    Sun, Wenli
    CURRENT PHARMACEUTICAL ANALYSIS, 2023, 19 (04) : 267 - 281
  • [3] Are multi-omics enough?
    Cristina Vilanova
    Manuel Porcar
    Nature Microbiology, 1 (8)
  • [4] Are multi-omics enough?
    Vilanova, Cristina
    Porcar, Manuel
    NATURE MICROBIOLOGY, 2016, 1 (08)
  • [5] CLINICAL MULTI-OMICS
    Radstake, Timothy R.
    ANNALS OF THE RHEUMATIC DISEASES, 2019, 78 : 16 - 16
  • [6] Spatial multi-omics: deciphering technological landscape of integration of multi-omics and its applications
    Liu, Xiaojie
    Peng, Ting
    Xu, Miaochun
    Lin, Shitong
    Hu, Bai
    Chu, Tian
    Liu, Binghan
    Xu, Yashi
    Ding, Wencheng
    Li, Li
    Cao, Canhui
    Wu, Peng
    JOURNAL OF HEMATOLOGY & ONCOLOGY, 2024, 17 (01)
  • [7] Omics and Multi-Omics in IBD: No Integration, No Breakthroughs
    Fiocchi, Claudio
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (19)
  • [8] Multi-Omics Profiling for Health
    Babu, Mohan
    Snyder, Michael
    MOLECULAR & CELLULAR PROTEOMICS, 2023, 22 (06)
  • [9] Bridging the multi-omics gap
    Attwaters, Michael
    NATURE REVIEWS GENETICS, 2023, 24 (08) : 488 - 488
  • [10] Endocrinology in the multi-omics era
    Smadar Shilo
    Eran Segal
    Nature Reviews Endocrinology, 2024, 20 : 73 - 74
12345