Efficient derivation of microglia-like cells from human pluripotent stem cells

被引：0

作者：

Julien Muffat

Yun Li

Bingbing Yuan

Maisam Mitalipova

Attya Omer

Sean Corcoran

Grisilda Bakiasi

Li-Huei Tsai

Patrick Aubourg

Richard M Ransohoff

Rudolf Jaenisch

机构：

[1] Whitehead Institute for Biomedical Research,Department of Biology

[2] University of Paris-Sud,Department of Brain and Cognitive Sciences

[3] Institut National de la Santé et de la Recherche Médicale U1169,undefined

[4] Massachusetts Institute of Technology,undefined

[5] Bryn Mawr College,undefined

[6] Picower Institute for Learning and Memory,undefined

[7] Massachusetts Institute of Technology,undefined

[8] GTDesign,undefined

[9] Biogen,undefined

来源：

Nature Medicine | 2016年 / 22卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

A protocol is developed to enable the differentiation of microglial-like cells from human pluripotent stem cells, which are shown to resemble primary human microglia, integrate into 3D neuronal cultures, and perform phagocytic and injury-response functions.

引用

页码：1358 / 1367

页数：9

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