Efficient derivation of microglia-like cells from human pluripotent stem cells

被引：0
|
作者：
Julien Muffat
Yun Li
Bingbing Yuan
Maisam Mitalipova
Attya Omer
Sean Corcoran
Grisilda Bakiasi
Li-Huei Tsai
Patrick Aubourg
Richard M Ransohoff
Rudolf Jaenisch
机构：
[1] Whitehead Institute for Biomedical Research,Department of Biology
[2] University of Paris-Sud,Department of Brain and Cognitive Sciences
[3] Institut National de la Santé et de la Recherche Médicale U1169,undefined
[4] Massachusetts Institute of Technology,undefined
[5] Bryn Mawr College,undefined
[6] Picower Institute for Learning and Memory,undefined
[7] Massachusetts Institute of Technology,undefined
[8] GTDesign,undefined
[9] Biogen,undefined
来源：
Nature Medicine | 2016年 / 22卷
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学科分类号：
摘要：
A protocol is developed to enable the differentiation of microglial-like cells from human pluripotent stem cells, which are shown to resemble primary human microglia, integrate into 3D neuronal cultures, and perform phagocytic and injury-response functions.
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页码：1358 / 1367
页数：9
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