Synthesis of mesityl-substituted 1,3,4-oxadiazoles from mesitotrichloride and aromatic and heteroaromatic acid hydrazides

被引：0
|
作者：
Belen'kii L.I. [1 ]
Luiksaar S.I. [1 ]
Krayushkin M.M. [1 ]
机构：
[1] N. D. Zelinskii Institute of Organic Chemistry
来源：
Chemistry of Heterocyclic Compounds | 1999年 / 35卷 / 4期
关键词：
Mass Spectrum; Organic Chemistry; Hydrazide; Acid Hydrazide; Reductive Condensation;
D O I：
10.1007/BF02319340
中图分类号：
学科分类号：
摘要：
At interaction of 2,4,6-trimethylbenzotrichloride with aromatic (heteroaromatic) acid hydrazides in a mixture of 2,6-lutidine and tert-butanol the processes of alcoholysis and reductive condensation are suppressed. The corresponding 2-aryl- or 2-hetaryl-5-mesityl-1,3,4-oxadiazoles are obtained in high yields. The PMR, IR, and mass spectra of the products are studied. ©1999 KluwerAcademic/Plenum Publishers.
引用
收藏
页码：492 / 498
页数：6
相关论文
共 50 条
  • [31] Synthesis of branched polynuclear 1,3,4-oxadiazoles
    Vereshchagin, L. I.
    Verkhozina, O. N.
    Proidakov, A. G.
    Smirnov, A. I.
    Kizhnyaev, V. N.
    CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2008, 44 (09) : 1158 - 1163
  • [32] An efficient synthesis of new 2-aminomethyl-1,3,4-oxadiazoles from enantiomeric phenylglycine hydrazides
    Kudelko, Agnieszka
    Zielinski, Wojciech
    TETRAHEDRON, 2009, 65 (06) : 1200 - 1206
  • [33] DIMETHYLDICHLOROSILANE AS REAGENT FOR THE SYNTHESIS OF 1,3,4-OXADIAZOLES FROM DIAROYLHYDRAZINES
    CHIRIAC, CI
    REVUE ROUMAINE DE CHIMIE, 1987, 32 (02) : 223 - 226
  • [34] Synthesis and characterization of nitroaryl substituted bis-1,3,4-oxadiazoles
    Sikder, N
    Bulakh, NR
    Mehilal
    Sikder, AK
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2002, 12 (01) : 29 - 32
  • [35] SYNTHESIS, CRYSTAL STRUCTURES AND ELECTROCHEMISTRY OF FERROCENYL-SUBSTITUTED 1,3,4-OXADIAZOLES
    Tauchman, Jiri
    Trnka, Jakub
    Cisarova, Ivana
    Stepnicka, Petr
    COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 2010, 75 (10) : 1023 - 1040
  • [36] Design, Synthesis and Cytotoxicity Evalufation of Substituted Benzimidazole Conjugated 1,3,4-Oxadiazoles
    Nguyen Phu Quy
    Bui Thi Buu Hue
    Kiep Minh Do
    Ha Thi Kim Quy
    Tran Quang De
    Tran Thi Bich Phuong
    Pham Cong Trang
    Nguyen Cuong Quoc
    Morita, Hiroyuki
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2022, 70 (06) : 448 - 453
  • [37] Reactions of α-mercaptocarboxylic acid hydrazides with triethyl orthoesters: synthesis of 1,3,4-thiadiazin-5(6H)-ones and 1,3,4-oxadiazoles
    Kudelko, Agnieszka
    TETRAHEDRON, 2012, 68 (18) : 3616 - 3625
  • [38] Synthesis and Biological Evaluation of β-Aroylpropionic acid based 1,3,4-Oxadiazoles
    Husain, A.
    Ahuja, Priyanka
    Sarafroz
    INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2009, 71 (01) : 62 - 66
  • [39] PHOSPHORUS-ACID IODINE AS REAGENT FOR THE SYNTHESIS OF 1,3,4-OXADIAZOLES FROM DIACYLHYDRAZINES
    CHIRIAC, CI
    REVUE ROUMAINE DE CHIMIE, 1986, 31 (02) : 159 - 162
  • [40] Microwave irradiation promoted reactions of orthoesters with carboxylic acid hydrazides. Preparation of 1,3,4-oxadiazoles
    Khajavi, MS
    Hosseini, SSS
    Sefidkon, F
    IRANIAN JOURNAL OF CHEMISTRY & CHEMICAL ENGINEERING-INTERNATIONAL ENGLISH EDITION, 1997, 16 (02): : 68 - 71
12345