Epileptogenesis in the immature brain: emerging mechanisms

被引:0
|
作者
Sanjay N. Rakhade
Frances E. Jensen
机构
[1] Children's Hospital and Harvard Medical School,Department of Neurology, Division of Neuroscience
来源
关键词
D O I
暂无
中图分类号
学科分类号
摘要
The developing brain is especially prone to seizure activity, and population studies have shown that seizure incidence peaks during the first month of life. Research into the factors responsible for this enhanced seizure susceptibility could yield potential therapeutic targets to prevent epileptogenesis and provide biomarkers to identify individuals who are at heightened risk of developing epilepsy.
引用
收藏
页码:380 / 391
页数:11
相关论文
共 50 条
  • [21] Neuronal mechanisms of epileptogenesis
    Di Maio, Roberto
    FRONTIERS IN CELLULAR NEUROSCIENCE, 2014, 8
  • [22] Immune mechanisms in epileptogenesis
    Xu, Dan
    Miller, Stephen D.
    Koh, Sookyong
    FRONTIERS IN CELLULAR NEUROSCIENCE, 2013, 7
  • [23] NMDA RECEPTOR INVOLVEMENT IN EPILEPTOGENESIS IN THE IMMATURE NEOCORTEX
    HABLITZ, JJ
    LEE, WL
    PRINCE, DA
    BENARI, Y
    EPILEPSY RESEARCH, 1992, : 139 - 145
  • [24] Mechanisms underlying blood-brain barrier dysfunction in brain pathology and epileptogenesis: Role of astroglia
    Kovacs, Richard
    Heinemann, Uwe
    Steinhaeuser, Christian
    EPILEPSIA, 2012, 53 : 53 - 59
  • [25] Maturational aspects of epilepsy mechanisms and consequences for the immature brain
    Sanchez, RM
    Jensen, FE
    EPILEPSIA, 2001, 42 (05) : 577 - 585
  • [26] Epileptogenesis in neonatal brain
    Katsarou, Anna-Maria
    Galanopoulou, Aristea S.
    Moshe, Solomon L.
    SEMINARS IN FETAL & NEONATAL MEDICINE, 2018, 23 (03): : 159 - 167
  • [27] Blood-brain barrier dysfunction in status epileptics: Mechanisms and role in epileptogenesis
    Swissa, Evyatar
    Serlin, Yonatan
    Vazana, Udi
    Prager, Ofer
    Friedmana, Alon
    EPILEPSY & BEHAVIOR, 2019, 101
  • [28] The emerging role of DNA methylation in epileptogenesis
    Kobow, Katja
    Bluemcke, Ingmar
    EPILEPSIA, 2012, 53 : 11 - 20
  • [29] Emerging Concepts in the Pathogenesis of Epilepsy and Epileptogenesis
    Dichter, Marc A.
    ARCHIVES OF NEUROLOGY, 2009, 66 (04) : 443 - 447
  • [30] Endogenous acetylcholine facilitates epileptogenesis in immature rat neocortex
    Potier, S
    Psarropoulou, C
    NEUROSCIENCE LETTERS, 2001, 302 (01) : 25 - 28