Epileptogenesis in the immature brain: emerging mechanisms

被引：0
|
作者：
Sanjay N. Rakhade
Frances E. Jensen
机构：
[1] Children's Hospital and Harvard Medical School,Department of Neurology, Division of Neuroscience
来源：
Nature Reviews Neurology | 2009年 / 5卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The developing brain is especially prone to seizure activity, and population studies have shown that seizure incidence peaks during the first month of life. Research into the factors responsible for this enhanced seizure susceptibility could yield potential therapeutic targets to prevent epileptogenesis and provide biomarkers to identify individuals who are at heightened risk of developing epilepsy.
引用
收藏
页码：380 / 391
页数：11
相关论文
共 50 条
  • [11] Effect of Resveratrol on Oxidative Stress and Mitochondrial Dysfunction in Immature Brain during Epileptogenesis
    Folbergrova, Jaroslava
    Jesina, Pavel
    Kubova, Hana
    Otahal, Jakub
    MOLECULAR NEUROBIOLOGY, 2018, 55 (09) : 7512 - 7522
  • [12] Effect of Resveratrol on Oxidative Stress and Mitochondrial Dysfunction in Immature Brain during Epileptogenesis
    Jaroslava Folbergrová
    Pavel Ješina
    Hana Kubová
    Jakub Otáhal
    Molecular Neurobiology, 2018, 55 : 7512 - 7522
  • [13] RESVERATROL ATTENUATES OXIDATIVE STRESS AND MITOCHONDRIAL DYSFUNCTION IN IMMATURE BRAIN DURING EPILEPTOGENESIS
    Folbergrova, J.
    Jesina, P.
    Kubova, H.
    Otahal, J.
    EPILEPSIA, 2017, 58 : S151 - S152
  • [14] Mechanisms and effects of seizures in the immature brain
    Nardou, Romain
    Ferrari, Diana C.
    Ben-Ari, Yehezkel
    SEMINARS IN FETAL & NEONATAL MEDICINE, 2013, 18 (04): : 175 - 184
  • [15] Barrier mechanisms in the brain, II. Immature brain
    Saunders, NR
    Habgood, MD
    Dziegielewska, KM
    CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 1999, 26 (02): : 85 - 91
  • [16] Mechanisms of epileptogenesis
    Najm, I
    Ying, Z
    Janigro, D
    NEUROLOGIC CLINICS, 2001, 19 (02) : 237 - +
  • [17] Epileptogenesis in the immature brain: Does treatment during status epilepticus (SE) make a difference?
    Suchomelova, L
    Baldwin, RA
    Wasterlain, CG
    ANNALS OF NEUROLOGY, 2005, 58 : S52 - S52
  • [18] Apoptotic Mechanisms in the Immature Brain: Involvement of Mitochondria
    Hagberg, Henrik
    Mallard, Carina
    Rousset, Catherine I.
    Wang, Xiaoyang
    JOURNAL OF CHILD NEUROLOGY, 2009, 24 (09) : 1141 - 1146
  • [19] Brain plasticity and cellular mechanisms of epileptogenesis in human and experimental cortical dysplasia
    Babb, TL
    Ying, Z
    Mikuni, N
    Nishiyama, K
    Drazba, J
    Bingaman, W
    Wyllie, E
    Wylie, CJ
    Yacubova, K
    EPILEPSIA, 2000, 41 : S76 - S81
  • [20] Unorthodox mechanisms of epileptogenesis
    Janigro, Damir
    de Curtis, Marco
    Marchi, Nicola
    Friedman, Alon
    EPILEPSIA, 2006, 47 : 375 - 375
12345