Synthesis of lupane triterpenoids with triphenylphosphonium substituents and studies of their antitumor activity

被引：0
|
作者：
A. Yu. Spivak
D. A. Nedopekina
E. R. Shakurova
R. R. Khalitova
R. R. Gubaidullin
V. N. Odinokov
U. M. Dzhemilev
Yu. P. Bel’skii
N. V. Bel’skaya
S. A. Stankevich
E. V. Korotkaya
V. A. Khazanov
机构：
[1] Russian Academy of Sciences,Institute of Petrochemistry and Catalysis
[2] Innovative Pharmacology Research (IPHAR),undefined
来源：
Russian Chemical Bulletin | 2013年 / 62卷
关键词：
lupane triterpenoids; betulinic acid; triphenylphosphonium compounds; anticancer compounds;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
New derivatives of lupane triterpenoids, viz., 20,29-dihydrobetulinic and 3-epi-20,29-dihydrobetulinic acid derivatives containing triphenylphosphonium fragments as substituents were synthesized. These compound considerably exceed betulinic acid in antitumor activity.
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页码：188 / 198
页数：10
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