The controversial role of Sirtuins in tumorigenesis — SIRT7 joins the debate

被引：0
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作者：
Ling Li
Ravi Bhatia
机构：
[1] City of Hope National Medical Center,Division of Hematopoietic Stem cell and Leukemia Research
来源：
Cell Research | 2013年 / 23卷
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摘要：
Sirtuins are NAD-dependent deacetylases that are conserved from yeast to mammals. A new report sheds light on the function of SIRT7, the least understood member of the Sirtuin family by identifying its locus-specific H3K18 deacetylase activity, and linking it to maintenance of cellular transformation in malignancies.
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页码：10 / 12
页数：2
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