Benzodiazepine-Like Substances and Hepatic EncephalopathyImplications for Treatment

被引：0

作者：

Jill A. Cossar

Peter C. Hayes

Ronan E. O’Carroll

机构：

[1] Edinburgh Royal Infirmary,Department of Medicine

[2] University of Stirling,Psychology Department

来源：

CNS Drugs | 1997年 / 8卷

关键词：

Hepatic Encephalopathy; Flumazenil; Fulminant Hepatic Failure; Gamma Amino Butyric Acid; Visual Evoke Response;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Hepatic encephalopathy is a neuropsychiatric syndrome that can complicate acute and chronic liver disease. Recent research has focused on the role benzodiazepine-like substances play in the pathogenesis of this disorder. It has been proposed that potentiation of the action of the neuroinhibitory transmitter γr-aminobutyric acid (GABA) through the binding of endogenous benzodiazepine agonists to the benzodiazepine receptor binding site accounts for the clinical and biochemical features of this condition.

引用

页码：91 / 101

页数：10

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