Benzodiazepine-Like Substances and Hepatic EncephalopathyImplications for Treatment

被引：0
|
作者：
Jill A. Cossar
Peter C. Hayes
Ronan E. O’Carroll
机构：
[1] Edinburgh Royal Infirmary,Department of Medicine
[2] University of Stirling,Psychology Department
来源：
CNS Drugs | 1997年 / 8卷
关键词：
Hepatic Encephalopathy; Flumazenil; Fulminant Hepatic Failure; Gamma Amino Butyric Acid; Visual Evoke Response;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Hepatic encephalopathy is a neuropsychiatric syndrome that can complicate acute and chronic liver disease. Recent research has focused on the role benzodiazepine-like substances play in the pathogenesis of this disorder. It has been proposed that potentiation of the action of the neuroinhibitory transmitter γr-aminobutyric acid (GABA) through the binding of endogenous benzodiazepine agonists to the benzodiazepine receptor binding site accounts for the clinical and biochemical features of this condition.
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页码：91 / 101
页数：10
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