A tandem Petasis-Ugi multi component condensation reaction: solution phase synthesis of six dimensional libraries

被引：56
|
作者：
Portlock, DE
Ostaszewski, R
Naskar, D
West, L
机构：
[1] Procter & Gamble Pharmaceut Hlth Care Res Ctr, Combinatorial Chem Sect, Mason, OH 45040 USA
[2] Warsaw Univ Technol, PL-00664 Warsaw, Poland
[3] Chembiotek Res Int, Salt Lake City 700091, Calcutta, India
来源：
TETRAHEDRON LETTERS | 2003年 / 44卷 / 03期
关键词：
D O I：
10.1016/S0040-4039(02)02619-9
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Amino acids with three points of diversity generated from the Petasis boronic acid-Mannich reaction can be used as one of the four components of the Ugi condensation to prepare six dimensional libraries of dipeptide amides. (C) 2002 Published by Elsevier Science Ltd.
引用
收藏
页码：603 / 605
页数：3
相关论文
共 50 条
  • [31] Ugi Four-Component Reaction Based on in-situ Capture of Isocyanide and Post-Modification Tandem Reaction: One-Pot Synthesis of Nitrogen Heterocycles
    Luo, Xianghao
    Xie, Yibi
    Huang, Nianyu
    Wang, Long
    [J]. CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2022, 42 (03) : 838 - 846
  • [32] Synthesis and conformational analysis of constrained β-turn mimetics incorporating a bicyclic turn inducer by use of the petasis three-component reaction on solid phase
    Danieli, Elisa
    Trabocchi, Andrea
    Menchi, Gloria
    Guarna, Antonio
    [J]. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2007, 2007 (10) : 1659 - 1668
  • [33] Applications of N-BOC-diamines for the solution phase synthesis of ketopiperazine libraries utilizing a Ugi/De-BOC/Cyclization (UDC) strategy
    Hulme, C
    Peng, J
    Louridas, B
    Menard, P
    Krolikowski, P
    Kumar, NV
    [J]. TETRAHEDRON LETTERS, 1998, 39 (44) : 8047 - 8050
  • [34] Complementary solid phase methods for the synthesis of Freidinger lactams: Application of Fukuyama's amine synthesis and application of a tandem UGI reaction ring closing metathesis process
    Miller, JF
    Koch, K
    Piscopio, AD
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1997, 214 : 67 - ORGN
  • [35] 4-COMPONENT CONDENSATION (UGI REACTION) AT HIGH-PRESSURE - NOVEL SYNTHESIS OF PEPTIDES CONTAINING VERY BULKY ALPHA,ALPHA-DISUBSTITUTED GLYCINES
    YAMADA, T
    YANAGI, T
    OMOTE, Y
    MIYAZAWA, T
    KUWATA, S
    SUGIURA, M
    MATSUMOTO, K
    [J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1990, (22) : 1640 - 1641
  • [36] Ugi four-center three-component reaction for the parallel solid-phase synthesis of N-substituted thiomopholinones
    Liu, Zhang
    Nefzi, Adel
    [J]. TETRAHEDRON LETTERS, 2012, 53 (09) : 1013 - 1014
  • [37] Tandem synthesis of functionalized hexaalkyl benzoisoquinolinopyrrolonaphthyridine-hexacarboxylate, via isoquinoline based multi-component reaction
    Piltan, Mohammad
    Yavari, Issa
    Moradi, Loghman
    [J]. CHINESE CHEMICAL LETTERS, 2013, 24 (11) : 979 - 983
  • [38] Tandem synthesis of functionalized hexaalkyl benzoisoquinolinopyrrolonaphthyridine-hexacarboxylate, via isoquinoline based multi-component reaction
    Mohammad Piltan
    Issa Yavari
    Loghman Moradi
    [J]. Chinese Chemical Letters, 2013, 24 (11) : 979 - 983
  • [39] An efficient synthesis of tetrahydropyrazolopyridine derivatives by a one-pot tandem multi-component reaction in a green media
    Dabiri, Minoo
    Salehi, Peyman
    Koohshari, Majid
    Hajizadeh, Zoleikha
    MaGee, David Ian
    [J]. ARKIVOC, 2014, : 204 - 214
  • [40] One-pot three-component tandem reaction: Synthesis of aryl/alkyl cyanamides libraries and their further conversion into tetrazole derivatives
    Mandapati, Usharani
    Mandapati, Pavan
    Pinapati, Srinivasarao
    Tamminana, Ramana
    Rudraraju, Rameshraju
    [J]. SYNTHETIC COMMUNICATIONS, 2018, 48 (05) : 500 - 510
12345