One-pot three-component tandem reaction: Synthesis of aryl/alkyl cyanamides libraries and their further conversion into tetrazole derivatives

被引:12
|
作者
Mandapati, Usharani [1 ]
Mandapati, Pavan [2 ]
Pinapati, Srinivasarao [1 ]
Tamminana, Ramana [3 ]
Rudraraju, Rameshraju [1 ]
机构
[1] Acharya Nagarjuna Univ, Dept Chem, Guntur 522510, Andhra Pradesh, India
[2] Univ Manitoba, Dept Chem, Winnipeg, MB, Canada
[3] GITAM Univ, Dept Chem, Bengaluru, Karnataka, India
关键词
Copper catalyst; desulphurization; mild reaction conditions; room temperature; substituted cyanamides; tandem reaction; AZIDE-ALKYNE CYCLOADDITION; CLICK-CHEMISTRY; 1,3-DIPOLAR CYCLOADDITIONS; HUISGEN CYCLOADDITION; LIGATION; 1,2,3-TRIAZOLES; TRANSFORMATION; CATALYSTS; POLYMER; ACIDS;
D O I
10.1080/00397911.2017.1402349
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
We have developed methodology for the synthesis of aryl/alkyl cyanamides from amines in one-pot four steps reaction using cheap, readily available and air stable copper source as catalyst under mild reaction conditions. We have also studied the application of cyanamides. In this connection, we could construct aryl tetrazolamine from cyanamides using click reaction [GRAPHICS] .
引用
收藏
页码:500 / 510
页数:11
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