Three-component one-pot reaction for the synthesis of β-amide ketones

被引:3
|
作者
Luo, Yan-Ping [1 ]
Chen, Qiong [2 ]
机构
[1] Hainan Univ, Key Lab Protect & Dev Utilisat Trop Crop Germplas, Minist Educ, Haikou 570228, Peoples R China
[2] Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Coll Chem, Wuhan 430079, Peoples R China
基金
中国国家自然科学基金;
关键词
beta-amide ketones; one-pot reaction; synthesis; DAKIN-WEST REACTION; ACETAMIDO KETONES; EFFICIENT; CATALYST; PROPARGYLAMINES; ALDEHYDES; ALKYNES; ACIDS;
D O I
10.2478/s11696-013-0313-0
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
beta-amide ketones were synthesised by a three-component one-pot reaction of phenylacetylene, aldehydes, and amides in anhydrous acetonitrile containing trifluoroacetic acid and acetic acid in the presence of AlCl3 catalyst. The title compound structures were identified by H-1 NMR, C-13 NMR, MS, and elemental analysis.
引用
收藏
页码:532 / 537
页数:6
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