Asymmetric synthesis of C-6 substituted pipecolic acid derivatives

被引:18
|
作者
Carbonnel, S [1 ]
Fayet, C [1 ]
Gelas, J [1 ]
Troin, Y [1 ]
机构
[1] Univ Blaise Pascal, Ecole Natl Super Chim Clermont Ferrance, Lab Chim Heterocycles & Glucides, F-63174 Aubiere, France
关键词
asymmetric synthesis; piperidines; pipecolic acid;
D O I
10.1016/S0040-4039(00)01463-5
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The synthesis of C-6 substituted pipecolic acid derivatives using an intramolecular Mannich-type reaction is described. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:8293 / 8296
页数:4
相关论文
共 50 条
  • [21] Preparation of c-6 substituted chitin derivatives under homogeneous conditions
    Zou, YQ
    Khor, E
    [J]. BIOMACROMOLECULES, 2005, 6 (01) : 80 - 87
  • [22] Synthesis and structural characterization of the C-6 fluoroalkylated pyrimidine derivatives
    Kristafor, Svjetlana
    Gazivoda, Tatjana
    Cetina, Mario
    Makuc, Damjan
    Plavec, Janez
    Raic-Malic, Silvana
    [J]. JOURNAL OF MOLECULAR STRUCTURE, 2009, 923 (1-3) : 19 - 23
  • [23] An efficient, asymmetric synthesis of pipecolic acid and 2-alkyl pipecolic acids
    Hou, DR
    Hung, SY
    Hu, CC
    [J]. TETRAHEDRON-ASYMMETRY, 2005, 16 (23) : 3858 - 3864
  • [24] Synthesis of curdlan derivatives regioselectively aminated at the C-6 position
    Zhang, Ruoran
    Edgar, Kevin J.
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2014, 247
  • [25] STEREOSPECIFIC SYNTHESIS OF C-6(7) METHOXYPENICILLIN AND METHOXYCEPHALOSPORIN DERIVATIVES
    JEN, T
    FRAZEE, J
    HOOVER, JRE
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1973, 38 (16): : 2857 - 2859
  • [26] Synthesis and structural studies of C-5 aryl- and C-6 alkyl-substituted pyrimidine derivatives
    Gazivoda, Tatjana
    Kristafor, Svjetlana
    Cetina, Mario
    Nagl, Ante
    Raic-Malic, Silvana
    [J]. STRUCTURAL CHEMISTRY, 2008, 19 (03) : 441 - 449
  • [27] Synthesis and structural studies of C-5 aryl- and C-6 alkyl-substituted pyrimidine derivatives
    Tatjana Gazivoda
    Svjetlana Krištafor
    Mario Cetina
    Ante Nagl
    Silvana Raić-Malić
    [J]. Structural Chemistry, 2008, 19 : 441 - 449
  • [28] Route selection in the synthesis of C-4 and C-6 substituted thienopyrimidines
    Bugge, Steffen
    Kaspersen, Svein Jacob
    Sundby, Eirik
    Hoff, Bard Helge
    [J]. TETRAHEDRON, 2012, 68 (45) : 9226 - 9233
  • [29] Design, synthesis, and evaluation of antitumor activity of novel C-6 sulfhydryl-substituted and 20-substituted derivatives of celastrol
    Su, Di
    Wei, Rong-yuan
    Yan, Zhi-ming
    Zhong, Guo-hui
    Qin, Xiang-qing
    Huang, Shu-tong
    Long, Juan-yue
    Zhang, Feng-ling
    He, Ping
    Chen, Zhong-ji
    Yan, Ya-qian
    Jiang, Neng
    Tang, Wei-zhong
    [J]. CHEMICAL BIOLOGY & DRUG DESIGN, 2023, 102 (02) : 316 - 331
  • [30] SUBSTITUTED PENICILLINS AND CEPHALOSPORINS .2. C-6(7)-ALKYL DERIVATIVES
    FIRESTONE, RA
    SCHELECH.N
    JOHNSTON, DB
    CHRISTEN.BG
    [J]. TETRAHEDRON LETTERS, 1972, (05) : 375 - +