An efficient, asymmetric synthesis of pipecolic acid and 2-alkyl pipecolic acids

被引:18
|
作者
Hou, DR [1 ]
Hung, SY
Hu, CC
机构
[1] Natl Cent Univ, Dept Chem, Taoyuan 320, Taiwan
[2] Natl Univ Kaohsiung, Dept Appl Chem, Kaohsiung 811, Taiwan
关键词
D O I
10.1016/j.tetasy.2005.10.025
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Both (R)- and (S)-pipecolic acids and their 2-alkyl derivatives have been synthesized via diastereoselective alkylations of (R)-5-phenylmorpholin-2-one 5. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:3858 / 3864
页数:7
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