Eliminative Deoxofluorination Using XtalFluor-E: A One-Step Synthesis of Monofluoroalkenes from Cyclohexanone Derivatives

被引：14
|
作者：
Vandamme, Mathilde [1 ]
Paquin, Jean-Francois [1 ]
机构：
[1] Univ Laval, Dept Chim, PROTEO, CGCC, 1045 Ave Med, Quebec City, PQ G1V 0A6, Canada
来源：
ORGANIC LETTERS | 2017年 / 19卷 / 13期
基金：
加拿大自然科学与工程研究理事会;
关键词：
IN-SITU ACTIVATION; CYCLODEHYDRATION AGENT; CARBOXYLIC-ACIDS; BENZYL ALCOHOLS; FLUORINATION; FLUOROALKENES; METATHESIS; OLEFINATION; FLUORIDES; EFFICIENT;
D O I：
10.1021/acs.orglett.7b01581
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The eliminative deoxofluorination of cyclohexanone derivatives using XtalFluor-E is described. The corresponding monofluoroalkenes are obtained in up to 79% yield. Notably, this one-step procedure occurs at room temperature using readily accessible and cost-effective reagents.
引用
收藏
页码：3604 / 3607
页数：4
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