XtalFluor-E: An Efficient Reagent for Synthesis of Oxazolines from Carboxylic Acids and O-Silylated Amino Alcohols

被引：4
|
作者：
Kumar, Vadiga Shanthi [1 ]
Gudise, Veera Babu [1 ]
Reddy, Eeda Koti [1 ]
Anwar, Shaik [1 ]
机构：
[1] Vignans Fdn Sci Technol & Res VFSTR Deemed Univ, Dept Sci & Humanities, Div Chem, Guntur 522213, Andhra Pradesh, India
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2019年 / 56卷 / 10期
关键词：
CROSS-COUPLING REACTION; ONE-STEP SYNTHESIS; FACILE PREPARATION; CHIRAL OXAZOLINES; INDPHOX-LIGANDS; CHEMISTRY; ACETYLCHOLINESTERASE; 1,3,4-OXADIAZOLES; (-)-THIANGAZOLE; 2-OXAZOLINES;
D O I：
10.1002/jhet.3642
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient protocol has been developed for the synthesis of 2-oxazolines from carboxylic acids and silylated amino alcohols. The advantage of this method was demonstrated by preparing O-silylated amino alcohols. The reaction proceeds via in situ desilylation of O-silylated amide followed by cyclization. Studies on silyl deprotection were carried out to explain yield for 2-oxazolines.
引用
收藏
页码：2753 / 2760
页数：8
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