Snapshot Coherence Tomographic Imaging

We demonstrate a high-throughput computation-efficient snapshot coherence tomographic imaging method by combining interferometric coding and compressive sampling. We first encode the depth distribution of a three-dimensional (3D) object into the spectrum of a light field, using the principle of optical coherence tomography (OCT), i.e., through a Michaelson interferometer, which generates an intermediate (x, y, lambda) data-cube that encodes the raw (x, y, z) data of the object. We then sample the spectral data using a well-established compressive spectral imaging technique, called the coded aperture snapshot spectral imaging (CASSI), which yields a compressed 2D (x, y) measurement that captures the whole 3D tomographic information of the object. Finally, a developed iterative algorithm and end-to-end deep learning network are used for tomographic reconstruction from the single 2D measurement. Such integration of OCT and CASSI leads to a physically simple and computationally efficient system, allowing us to implement a large data size of more than 2000 x 2000 pixels in the transverse dimensions and up to 200 pixels (depth slices) in the axial dimension. Owning to the interferometry-based depth sensing mechanism, we achieve a high axial resolution of up to 13 mu m within an axial field of view of 1.6 mm. Video-rate visualization of dynamic 3D objects at micrometer scale are shown through several examples.