Design, radio-synthesis and evaluation of a novel [18F]-TKP for noninvasive PET imaging of brain Aβ deposits and neurofibrillary tangles

被引：0
|
作者：
Kong, Yanyan [2 ]
Hua, Fengchun [2 ]
Guan, Yihui [2 ]
Zhao, Bizeng [1 ]
机构：
[1] Jiaotong Univ, Shanghai Peoples Hosp 6, Shanghai, Peoples R China
[2] Fudan Univ, Huashan Hosp, PET Ctr, Shanghai, Peoples R China
来源：
JOURNAL OF NUCLEAR MEDICINE | 2016年 / 57卷
基金：
中国国家自然科学基金;
关键词：
D O I：
暂无
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
1030
引用
收藏
页数：2
相关论文
共 50 条
  • [31] Preclinical evaluation and first-in-human dosimetry of [18F]MK-6240, a new PET tracer for in vivo quantification of human neurofibrillary tangles
    Lohith, Talakad
    Bennacef, Idriss
    Zeng, Zhizhen
    Holahan, Marie
    Koole, Michel
    Van Laere, Koen
    Sur, Cyrille
    Struyk, Arie
    Walji, Abbas
    Hostetler, Eric
    JOURNAL OF NUCLEAR MEDICINE, 2016, 57
  • [32] Rapid and efficient synthesis of [18F]fluoronicotinamides, [18F]fluoroisonicotinamides and [18F]fluorobenzamides as potential pet radiopharmaceuticals for melanoma imaging
    Al Jammaz, I.
    Al-Otaibi, B.
    Okarvi, S.
    Amartey, J.
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2011, 54 (06): : 312 - 317
  • [33] The synthesis and in vivo evaluation of [18F]PF-9811: a novel PET ligand for imaging brain fatty acid amide hydrolase (FAAH)
    Skaddan, Marc B.
    Zhang, Lei
    Johnson, Douglas S.
    Zhu, Aijun
    Zasadny, Kenneth R.
    Coelho, Richard V.
    Kuszpit, Kyle
    Currier, Gwen
    Fan, Kuo-Hsien
    Beck, Elizabeth M.
    Chen, Laigao
    Drozda, Susan E.
    Balan, Gayatri
    Niphakis, Micah
    Cravatt, Benjamin F.
    Ahn, Kay
    Bocan, Thomas
    Villalobos, Anabella
    NUCLEAR MEDICINE AND BIOLOGY, 2012, 39 (07) : 1058 - 1067
  • [34] First Synthesis of [18F]Hexafluorophosphate ([18F]HFP) and In Vivo Evaluation as PET Reporter Probe for Sodium/Iodide Symporter Imaging
    Jiang, Huailei
    Bansal, Aditya
    Goyal, Ribu
    Degrado, Timothy
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2017, 60 : S60 - S60
  • [35] Synthesis of β-configured clickable [18F]FDGs as novel 18F-fluoroglycosylation tools for PET in vivo imaging
    Elgland, Mathias
    Nordeman, Patrik
    Fyrner, Timmy
    Konradsson, Peter
    Antoni, Gunnar
    Nilsson, Peter
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253
  • [36] Synthesis and evaluation of [18F]fluororasagiline, a novel PET radioligand for MAO-B
    Nag, Sangram
    Lehmann, Lutz
    Kettschau, Georg
    Thiele, Aandrea
    Varrone, Andrea
    Gulyas, Balazs
    Halldin, Christer
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2011, 54 : S269 - S269
  • [37] PET imaging of benzodiazepine receptors in the human brain:: Evaluation of [18F]fluoro-ethylflumazenil.
    Grunder, GM
    Siessmeier, T
    Piel, M
    Schirrmacher, R
    Lange-Asschenfeldt, C
    Vernaleken, I
    Buchholz, HG
    Stoeter, P
    Drzezga, A
    Luddens, H
    Bartenstein, P
    Roesch, F
    JOURNAL OF NUCLEAR MEDICINE, 2000, 41 (05) : 199P - 199P
  • [38] Evaluation of trans- and cis-4-[18F]Fluorogabapentin for Brain PET Imaging
    Zhou, Yu-Peng
    Normandin, Marc D.
    Belov, Vasily
    Macdonald-Soccorso, Marina T.
    Moon, Sung-Hyun
    Sun, Yang
    El Fakhri, Georges
    Guehl, Nicolas J.
    Brugarolas, Pedro
    ACS CHEMICAL NEUROSCIENCE, 2023, 14 (23): : 4208 - 4215
  • [39] Synthesis and biological evaluation of novel oxindole derivatives for imaging neurofibrillary tangles in Alzheimer's disease
    Watanabe, Hiroyuki
    Ono, Masahiro
    Kimura, Hiroyuki
    Matsumura, Kenji
    Yoshimura, Masashi
    Okamoto, Yoko
    Ihara, Masafumi
    Takahashi, Ryosuke
    Saji, Hideo
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 22 (17) : 5700 - 5703
  • [40] Novel [18F]fluoroethoxy- and [18F]fluoropropoxyindoleacetamides for imaging the TSPO 18kDa (PBR) with PET
    Damont, Annelaure
    Catarina, Tony
    Kuhnast, Bertrand
    Boisgard, Raphael
    Marguet, Frank
    Puech, Frederic
    Rooney, Thomas
    Tavitian, Bertrand
    Dolle, Frederic
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2011, 54 : S34 - S34
12345