The safety of atovaquone/proguanil in long-term malaria prophylaxis of nonimmune adults

被引：0
|
作者：
Petersen, E [1 ]
机构：
[1] Statens Serum Inst, Dept Gastrointestinal & Parasit Dis, World Hlth Org, Natl Malaria Diagnost Ref Ctr, DK-2300 Copenhagen, Denmark
来源：
JOURNAL OF TRAVEL MEDICINE | 2003年 / 10卷
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暂无
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Background. Data on the long-term safety of atovaquone/proguanil in nonimmune travelers are limited. Methods: An open-label study, involving 300 Danish soldiers stationed in Eritrea for 6 months was initiated. The subjects self-reported their symptoms on a post-travel questionnaire. The study compared the symptoms of compliers and noncompliers. Results: No serious adverse events occurred. Diarrhea, stomach pain, headache, cough, and loss of appetite were the most common symptoms reported. No case of Plasmodium falciparum malaria occurred. Conclusions: Atovaquone/proguanil was safe and well tolerated in this group of long-term nonimmune travelers.
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页码：S13 / S15
页数：3
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