The safety of atovaquone/proguanil in long-term malaria prophylaxis of nonimmune adults

被引：0

作者：

Petersen, E ^{[1
]}

机构：

[1] Statens Serum Inst, Dept Gastrointestinal & Parasit Dis, World Hlth Org, Natl Malaria Diagnost Ref Ctr, DK-2300 Copenhagen, Denmark

来源：

JOURNAL OF TRAVEL MEDICINE | 2003年 / 10卷

关键词：

D O I：

暂无

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Background. Data on the long-term safety of atovaquone/proguanil in nonimmune travelers are limited. Methods: An open-label study, involving 300 Danish soldiers stationed in Eritrea for 6 months was initiated. The subjects self-reported their symptoms on a post-travel questionnaire. The study compared the symptoms of compliers and noncompliers. Results: No serious adverse events occurred. Diarrhea, stomach pain, headache, cough, and loss of appetite were the most common symptoms reported. No case of Plasmodium falciparum malaria occurred. Conclusions: Atovaquone/proguanil was safe and well tolerated in this group of long-term nonimmune travelers.

引用

页码：S13 / S15

页数：3

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