Lymphangiogenesis: Molecular Mechanisms and Future Promise

被引：1084
|
作者：
Tammela, Tuomas [1 ,2 ]
Alitalo, Kari [1 ,2 ]
机构：
[1] Univ Helsinki, Lab Mol Canc Biol, FIN-00014 Helsinki, Finland
[2] Univ Helsinki, Haartman Inst, Biomedicum Helsinki, FIN-00014 Helsinki, Finland
来源：
CELL | 2010年 / 140卷 / 04期
关键词：
GROWTH-FACTOR-C; LYMPH-NODE LYMPHANGIOGENESIS; ENDOTHELIAL PROGENITOR CELLS; VEGF-C; BREAST-CANCER; TUMOR-METASTASIS; INFLAMMATORY LYMPHANGIOGENESIS; EMBRYONIC LYMPHANGIOGENESIS; PLATELET ACTIVATION; VESSEL DEVELOPMENT;
D O I：
10.1016/j.cell.2010.01.045
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The growth of lymphatic vessels (lymphangiogenesis) is actively involved in a number of pathological processes including tissue inflammation and tumor dissemination but is insufficient in patients suffering from lymphedema, a debilitating condition characterized by chronic tissue edema and impaired immunity. The recent explosion of knowledge on the molecular mechanisms governing lymphangiogenesis provides new possibilities to treat these diseases. © 2010 Elsevier Inc. All rights reserved.
引用
收藏
页码：460 / 476
页数：17
相关论文
共 50 条
  • [41] The promise of molecular staging for the future (vol 123, pg 728, 2017)
    Maxwell, G. L.
    Mutch, D. G.
    [J]. CANCER, 2017, 123 (19) : 3857 - 3857
  • [42] Molecular mechanisms of miR-1236 in the assessment of tumor lymphangiogenesis in human ovarian cancer patients
    Khademi, Mahsa
    Babaei, Zeinab
    Ghorbanhosseini, Seyedeh Sara
    Razavi, Amirnader Emami
    Aghaei, Mahmoud
    [J]. JOURNAL OF GENE MEDICINE, 2023, 25 (05):
  • [43] Molecular mechanisms and future uses of antiestrogens - Preface
    Jordan, VC
    Gradishar, WJ
    [J]. MOLECULAR ASPECTS OF MEDICINE, 1997, 18 (03) : 168 - +
  • [44] FUTURE PROMISE - INTRODUCTION
    MILLS, LO
    [J]. PASTORAL PSYCHOLOGY, 1977, 26 (01) : 3 - 3
  • [45] MENTORING - A PROMISE FOR THE FUTURE
    FREY, BR
    NOLLER, RB
    [J]. JOURNAL OF CREATIVE BEHAVIOR, 1986, 20 (01): : 49 - 51
  • [46] HDF promise for the future
    Lornoy, Willy
    De Meester, Johan
    [J]. NEPHROLOGY DIALYSIS TRANSPLANTATION, 2008, 23 (08) : 2705 - 2706
  • [47] SCO:Promise for Future
    Muhammad Asif Noor
    [J]. 中国新闻发布(英文版), 2023, (06) : 34 - 37
  • [48] Globalization: A Future with Promise
    Spitzer, Roxane
    [J]. NURSE LEADER, 2006, 4 (06) : 4 - 4
  • [49] CITY - PROMISE FOR FUTURE
    不详
    [J]. AMERICAN GAS ASSOCIATION MONTHLY, 1972, 54 (10): : 4 - &
  • [50] Haemodiafiltration: promise for the future?
    van der Weerd, Neelke C.
    Penne, E. Lars
    van den Dorpel, Marinus A.
    Grooteman, Muriel P. C.
    Nube, Menso J.
    Bots, Michiel L.
    ter Wee, Piet M.
    Blankestijn, Peter J.
    [J]. NEPHROLOGY DIALYSIS TRANSPLANTATION, 2008, 23 (02) : 438 - 443
12345