Synthesis and unexpected reactions of 2-hydroxy-3-pyridinylacetic hydrazides. Formation of 2H-pyrrolo[2,3-b]pyridin-2-ones

被引：9

作者：

Teleha, CA ^{[1
]}

Greenberg, RA ^{[1
]}

Chorvat, RJ ^{[1
]}

机构：

[1] Dupont Merck Pharmaceut Co, Chem & Phys Sci, Wilmington, DE 19880 USA

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1998年 / 35卷 / 01期

关键词：

D O I：

10.1002/jhet.5570350127

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of 2-hydroxy-3-pyridinylacetic hydrazides under mild mesylation conditions provided 2H-pyrrolo[2,3-b]pyridin-2-ones as unexpected products. This rearrangement is believed to result from an intramolecular attack of the hydrazide on a reactive pyridinium species formed under the reaction conditions.

引用

页码：145 / 149

页数：5

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