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Adult stem cells and other cancer residents. Part II
被引:0
|作者:
Sverdlov, E. D.
[1
]
Pleshkan, V. V.
[1
]
Alekseenko, I. V.
[1
]
Vinogradova, T. V.
[1
]
Kopantsev, E. P.
[1
]
Didych, D. A.
[1
]
机构:
[1] Russian Acad Sci, Shemyakin Ovchinnikov Inst Bioorgan Chem, Moscow 117997, Russia
基金:
俄罗斯科学基金会;
关键词:
cancer;
stem cells;
adult stem cells;
master genes;
transcription factors;
enhancers;
superenhancers;
transcription regulation;
PANCREATIC DUCTAL ADENOCARCINOMA;
MASTER TRANSCRIPTION FACTORS;
SUPER-ENHANCERS;
TGF-BETA;
GENE-EXPRESSION;
EMBRYONIC-DEVELOPMENT;
REGULATORY NETWORKS;
CHROMATIN STATE;
CELLULAR-ORIGIN;
HUMAN GENOME;
D O I:
10.3103/S0891416815040114
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
In this review, we have attempted to generalize recent data on adult stem cells as the most likely cells, according to the current dominant paradigm, in which a predisposition to malignant degeneration occurs or, in other words, where cancer is initiated.
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页码:157 / 164
页数:8
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