Adult stem cells and other cancer residents. Part II

被引:0
|
作者
Sverdlov, E. D. [1 ]
Pleshkan, V. V. [1 ]
Alekseenko, I. V. [1 ]
Vinogradova, T. V. [1 ]
Kopantsev, E. P. [1 ]
Didych, D. A. [1 ]
机构
[1] Russian Acad Sci, Shemyakin Ovchinnikov Inst Bioorgan Chem, Moscow 117997, Russia
基金
俄罗斯科学基金会;
关键词
cancer; stem cells; adult stem cells; master genes; transcription factors; enhancers; superenhancers; transcription regulation; PANCREATIC DUCTAL ADENOCARCINOMA; MASTER TRANSCRIPTION FACTORS; SUPER-ENHANCERS; TGF-BETA; GENE-EXPRESSION; EMBRYONIC-DEVELOPMENT; REGULATORY NETWORKS; CHROMATIN STATE; CELLULAR-ORIGIN; HUMAN GENOME;
D O I
10.3103/S0891416815040114
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In this review, we have attempted to generalize recent data on adult stem cells as the most likely cells, according to the current dominant paradigm, in which a predisposition to malignant degeneration occurs or, in other words, where cancer is initiated.
引用
收藏
页码:157 / 164
页数:8
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