Association between HLA-DR4 haplotypes and tuberculin skin test response in the Ache population

被引：6

作者：

Lindenau, J. D. ^{[1
]}

Guimaraes, L. S. P. ^{[2
]}

Hurtado, A. M. ^{[3
]}

Hill, K. R. ^{[3
]}

Tsuneto, L. T. ^{[4
]}

Salzano, F. M. ^{[1
]}

Petzl-Erler, M. L. ^{[5
]}

Hutz, M. H. ^{[1
]}

机构：

[1] Univ Fed Rio Grande do Sul, Inst Biociencias, Dept Genet, BR-91501970 Porto Alegre, RS, Brazil

[2] Hosp Clin Porto Alegre, Unidade Epidemiol & Estat, Porto Alegre, RS, Brazil

[3] Arizona State Univ, Sch Human Evolut & Social Change, Tempe, AZ USA

[4] Univ Estadual Maringa, Dept Anal Clin, Maringa, PR, Brazil

[5] Univ Fed Parana, Dept Genet, BR-80060000 Curitiba, PR, Brazil

来源：

TISSUE ANTIGENS | 2014年 / 84卷 / 05期

关键词：

Amerindians; anergy; human leukocyte antigen; tuberculin skin test response response; tuberculosis; HUMAN-LEUKOCYTE ANTIGEN; PULMONARY TUBERCULOSIS; HLA-DR; BALANCING SELECTION; IRANIAN PATIENTS; ALLELES; DQ; SUSCEPTIBILITY; INDIANS; GENES;

D O I：

10.1111/tan.12451

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The human leukocyte antigen (HLA) system has a major role in the regulation of the immune response as it is involved in the defense against pathogens. Evidence for association with tuberculosis (TB) is more consistent for class II than for class I HLA genes. TB is important among indigenous peoples in South America, not only because of its historical role in regional depopulation, but also because it is still widespread. The aim of this study was to evaluate the association of HLA class II alleles, haplotypes and genotypes and tuberculin skin test response (TST) in 76 individuals of the Ache population. Poisson Regression was employed to assess risk genotypes. DRB1*04, DQA1*03 and DQB1*03:02 were associated with TST response in this population.

引用

页码：479 / 483

页数：5

共 50 条

[31] Molecular mechanisms involved in the association of HLA-DR4 and rheumatoid arthritis
Isabelle Auger
Eric Toussirot
Jean Roudier
Immunologic Research, 1997, 16 : 121 - 126
[32] ASSOCIATION OF HLA-DR4 WITH IDIOPATHIC FOCAL SEGMENTAL GLOMERULOSCLEROSIS (FS)
GLICKLICH, D
HASKELL, L
AMERICAN JOURNAL OF KIDNEY DISEASES, 1986, 8 (06) : A7 - A7
[33] A SIMPLE NONRADIOACTIVE METHOD OF DNA TYPING FOR SUBSETS OF HLA-DR4 - PREVALENCE DATA ON HLA-DR4 SUBSETS IN 3 DIABETIC POPULATION GROUPS
JU, LY
GU, XF
BARDIE, R
KRISHNAMOORTHY, R
CHARRON, D
HUMAN IMMUNOLOGY, 1991, 31 (04) : 251 - 258
[34] HLA-DR4 ASSOCIATED RESPONSE TO CORTICOSTEROIDS IN GRAVES OPHTHALMOPATHY PATIENTS
VANDERGAAG, R
WIERSINGA, WM
KOORNNEEF, L
MOURITS, MP
PRUMMEL, MF
BERGHOUT, A
DEVRIES, RRP
SCHREUDER, GMT
DAMARO, J
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, 1990, 13 (06): : 489 - 492
[35] HETEROGENEITY OF HLA-DR4 IN GREEKS INCLUDING A UNIQUE DR4-DQW2 ASSOCIATION
AWAD, J
OLLIER, W
CUTBUSH, S
PAPASTERIADIS, C
GUPTA, A
CARTHY, D
MCCLOSKEY, D
BROWN, CJ
BOKI, K
FOSTIZOPOULOS, G
FESTENSTEIN, H
TISSUE ANTIGENS, 1990, 35 (01): : 40 - 44
[36] PREECLAMPSIA IS ASSOCIATED WITH HLA-DR4 SHARING BETWEEN MOTHER AND FETUS
KILPATRICK, DC
GIBSON, F
LIVINGSTON, J
LISTON, WA
TISSUE ANTIGENS, 1990, 35 (04): : 178 - 181
[37] HLA-DQ BETA-CHAIN POLYMORPHISM IN HLA-DR4 HAPLOTYPES ASSOCIATED WITH RHEUMATOID-ARTHRITIS
SINGAL, DP
REID, B
KASSAM, YB
DSOUZA, M
BENSEN, WG
ADACHI, JD
LANCET, 1987, 2 (8568): : 1118 - 1120
[38] HLA-DR4 allele and haplotype diversity in a hematopoietic cell transplant population
Smith, AG
Warnock, S
Regen, L
McKinney, S
Hanse, JA
HUMAN IMMUNOLOGY, 2004, 65 : S99 - S99
[39] HLA-DR4 AND PRIMARY BILIARY-CIRRHOSIS - A NEW DISEASE ASSOCIATION
CONNORS, CM
MILLER, KB
SIPERSKY, RA
KAPLAN, MM
GAROVOY, MR
HUMAN IMMUNOLOGY, 1981, 3 (04) : 357 - 358
[40] HLA-DR4 AND GM 1-21 HAPLOTYPES ARE ASSOCIATED WITH PSEUDOLUPUS INDUCED BY VENOPYRONUM DRAGEES
GROSSEWILDE, H
GENTH, E
GREVESMUHL, A
VOGELER, U
ZARNOWSKI, H
MIERAU, R
DOXIADIS, G
DOXIADIS, I
MAAS, D
ARTHRITIS AND RHEUMATISM, 1987, 30 (08): : 878 - 883

← 1 2 3 4 5 →