Bounds are given on the sire of the parameter-space decomposition induced by multiple sequence alignment problems where phylogenetic information may be given or inferred. It is shown that many of the usual formulations of these problems fall within the same integer parametric framework, implying that the number of distinct optima obtained as the parameters are varied across their ranges is polynomially bounded in the length and number of sequences.
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Department of Computer Science, Iowa State University, Ames, IA 50011, United StatesDepartment of Computer Science, Iowa State University, Ames, IA 50011, United States
Fernández-Baca, David
Seppäläinen, Timo
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Department of Mathematics, University of Wisconsin-Madison, Madison, WI 53706, United StatesDepartment of Computer Science, Iowa State University, Ames, IA 50011, United States
Seppäläinen, Timo
Slutzki, Giora
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Department of Computer Science, Iowa State University, Ames, IA 50011, United StatesDepartment of Computer Science, Iowa State University, Ames, IA 50011, United States
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Tel Aviv Univ, George S Wise Fac Life Sci, Dept Cell Res & Immunol, IL-69978 Tel Aviv, IsraelTel Aviv Univ, George S Wise Fac Life Sci, Dept Cell Res & Immunol, IL-69978 Tel Aviv, Israel
Ashkenazy, Haim
Sela, Itamar
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NIH, Natl Ctr Biotechnol Informat, Natl Lib Med, Bethesda, MD 20894 USATel Aviv Univ, George S Wise Fac Life Sci, Dept Cell Res & Immunol, IL-69978 Tel Aviv, Israel
Sela, Itamar
Karin, Eli Levy
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Tel Aviv Univ, George S Wise Fac Life Sci, Dept Cell Res & Immunol, IL-69978 Tel Aviv, Israel
Tel Aviv Univ, George S Wise Fac Life Sci, Dept Mol Biol & Ecol Plants, IL-69978 Tel Aviv, IsraelTel Aviv Univ, George S Wise Fac Life Sci, Dept Cell Res & Immunol, IL-69978 Tel Aviv, Israel
Karin, Eli Levy
Landan, Giddy
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Christian Albrechts Univ Kiel, Inst Microbiol, D-24118 Kiel, GermanyTel Aviv Univ, George S Wise Fac Life Sci, Dept Cell Res & Immunol, IL-69978 Tel Aviv, Israel
Landan, Giddy
Pupko, Tal
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Tel Aviv Univ, George S Wise Fac Life Sci, Dept Cell Res & Immunol, IL-69978 Tel Aviv, IsraelTel Aviv Univ, George S Wise Fac Life Sci, Dept Cell Res & Immunol, IL-69978 Tel Aviv, Israel
机构:
Univ Queensland, Australian Res Council, Ctr Bioinformat, Brisbane, Qld 4072, AustraliaUniv Queensland, Australian Res Council, Ctr Bioinformat, Brisbane, Qld 4072, Australia
Hohl, Michael
Ragan, Mark A.
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机构:Univ Queensland, Australian Res Council, Ctr Bioinformat, Brisbane, Qld 4072, Australia
机构:
Chonnam Natl Univ, Dept Stat, Fac Nat Sci, Gwangju, South KoreaChonnam Natl Univ, Dept Stat, Fac Nat Sci, Gwangju, South Korea
Ng, Chi-Tim
Li, Chun
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Chinese Univ Hong Kong, Dept Stat, Fac Sci, Hong Kong, Hong Kong, Peoples R China
Tianjin Univ Technol & Educ, Dept Stat, Fac Sci, Tianjin, Peoples R ChinaChonnam Natl Univ, Dept Stat, Fac Nat Sci, Gwangju, South Korea
Li, Chun
Fan, Xiaodan
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Chinese Univ Hong Kong, Dept Stat, Fac Sci, Hong Kong, Hong Kong, Peoples R ChinaChonnam Natl Univ, Dept Stat, Fac Nat Sci, Gwangju, South Korea