Microbiome: Focus on Causation and Mechanism

被引：165
|
作者：
Fischbach, Michael A. [1 ,2 ,3 ]
机构：
[1] Stanford Univ, Dept Bioengn, Stanford, CA 94305 USA
[2] Stanford Univ, ChEM H, Stanford, CA 94305 USA
[3] Chan Zuckerberg Biohub, Stanford, CA 94305 USA
来源：
CELL | 2018年 / 174卷 / 04期
关键词：
WIDE ASSOCIATION; GUT MICROBIOTA; COMMENSAL; HOST; INDIVIDUALS; ENGRAFTMENT; RESISTANCE; MODULATE; REVEALS; STRAINS;
D O I：
10.1016/j.cell.2018.07.038
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
There is tremendous enthusiasm for the microbiome in academia and industry. This Perspective argues that in order to realize its potential, the field needs to focus on establishing causation and molecular mechanism with an emphasis on phenotypes that are large in magnitude, easy to measure, and unambiguously driven by the microbiota.
引用
收藏
页码：785 / 790
页数：6
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