Mapping of new recessive cataract gene (lr2) in the mouse

被引：9
|
作者：
Song, CW
Okumoto, M
Mori, N
Kim, JS
Han, SS
Esaki, K
机构：
[1] UNIV OSAKA PREFECTURE, ADV SCI & TECHNOL RES INST, DEPT APPL BIOSCI, DIV BION, SAKAI, OSAKA 593, JAPAN
[2] KONKUK UNIV, DEPT VET MED, KWANGIJN KU, SEOUL 133701, SOUTH KOREA
[3] KONKUK UNIV, ANIM RESOURCES RES CTR, KWANGJIN KU, SEOUL 133701, SOUTH KOREA
[4] KOREA RES INST CHEM TECHNOL, TOXICOL RES CTR, TAEJON 305606, SOUTH KOREA
来源：
MAMMALIAN GENOME | 1997年 / 8卷 / 12期
关键词：
D O I：
10.1007/s003359900613
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A new strain of mice with cataracts was developed in BALB/cHeA and STS/A recombinant inbred strain, CXS4 (D). In this study the mapping of spontaneous autosomal recessive cataract mutation is described. This mutation was characterized by ruptures of the lens nucleus, vitreous chamber through the posterior capsule, and the vacuolization of the lens. For the linkage analysis, we produced two kinds of backcross progenies, (BALB/cHeA x D)F-1 and (STS/A x D)F-1 females crossed to D male mice. The gene (lr2, lens rupture2) was mapped to the central part of Chromosome(Chr) 14, 0.7 +/- 0.7cM from the micosatellite marker D14Mit28.
引用
收藏
页码：927 / 931
页数：5
相关论文
共 50 条
  • [11] Rupture of lens cataract: A novel hereditary recessive cataract model in the mouse
    Iida, F
    Matsushima, Y
    Hiai, H
    Uga, S
    Honda, Y
    EXPERIMENTAL EYE RESEARCH, 1997, 64 (01) : 107 - 113
  • [12] LR2型油船系泊与拖带设计研究
    杨利春
    黄志勇
    郭小天
    李静
    刘博
    张欣欣
    船舶标准化工程师, 2021, 54 (02) : 37 - 43
  • [13] Rupture of Lens Cataract: A Novel Hereditary Recessive Cataract Model in the Mouse
    Exp Eye Res, 1 (107):
  • [14] Fine mapping of autosomal recessive progressive cataract.
    Billingsley, GD
    Paterson, AD
    Munier, FL
    Balmer, A
    Schorderet, D
    Héon, E
    AMERICAN JOURNAL OF HUMAN GENETICS, 2001, 69 (04) : 517 - 517
  • [15] Enhanced heterogeneity of the LR2 segment in the human ribosomal intergenic spacer
    Kupriyanova, N. S.
    Shibalev, D. V.
    Voronov, A. S.
    Ryskov, A. P.
    GENE, 2008, 425 (1-2) : 44 - 47
  • [16] New Mutation in the Mouse Xpd/Ercc2 Gene Leads to Recessive Cataracts
    Kunze, Sarah
    Dalke, Claudia
    Fuchs, Helmut
    Klaften, Matthias
    Roessler, Ute
    Hornhardt, Sabine
    Gomolka, Maria
    Puk, Oliver
    Sabrautzki, Sibylle
    Kulka, Ulrike
    de Angelis, Martin Hrabe
    Graw, Jochen
    PLOS ONE, 2015, 10 (05):
  • [17] LR2 model for mobile satellite channels and its system performance analysis
    Li, Xing
    Wu, Shi-Qi
    Dianbo Kexue Xuebao/Chinese Journal of Radio Science, 2003, 18 (03):
  • [18] The LR2 model for mobile satellite channels and its system performance analysis
    Li, X
    Wu, SQ
    57TH IEEE VEHICULAR TECHNOLOGY CONFERENCE, VTC 2003-SPRING, VOLS 1-4, PROCEEDINGS, 2003, : 231 - 235
  • [19] Detection of intragenomic polymorphism of the LR2 region in the human ribosomal intergenic spacer
    Shibalev, DV
    Voronov, AS
    Firsov, SY
    Ryskov, AP
    Kupriyanova, NS
    MOLECULAR BIOLOGY, 2004, 38 (06) : 835 - 838
  • [20] Detection of Intragenomic Polymorphism of the LR2 Region in the Human Ribosomal Intergenic Spacer
    D. V. Shibalev
    A. S. Voronov
    S. Yu. Firsov
    A. P. Ryskov
    N. S. Kupriyanova
    Molecular Biology, 2004, 38 : 835 - 838
12345