Synthesis of new 4-aryl/alkyl-1-(5′,5′-diphenyl-4′-oxo-1′-H-4′,5′-dihydroimidazolidin-2′-yl)-3-hydroxy-1,2,4-triazolidine-5-thione derivatives as potential anti-cancer agents

被引：0
|
作者：
Datar, PA [1 ]
Shirodkar, PY [1 ]
Panikkar, KR [1 ]
机构：
[1] KM Kundnani Coll Pharm, Bombay 400018, Maharashtra, India
来源：
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2003年 / 42卷 / 03期
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D O I：
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中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
New 4-aryl/alkyl-1-(5',5'-diphenyl-4'-oxo- 1'H-4',5'-dihydroimidazolidin-2'-yl)-3-hydroxy-1,2,4-triazolidine-5-thiones 3 have been prepared by the reaction of 2-carbethoxy-(5',5'-diphenyl-4'-oxo-1'-H-4',5'-dihydroimidazolidin-2'-yl)-hydrazine 2 with various aryl/alkylisothiocyanates. Their anti-bacterial, anti-fungal, anthelmintic and anti-cancer activities are reported.
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页码：690 / 694
页数：5
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