One pot synthesis of 3-[2-(arylamino)thiazol-4-yl]coumarins in a three-component synthesis and a catalyst and solvent-free synthesis on grinding

被引：20
|
作者：
Chunduru, Venkata Sreenivasa Rao [1 ]
Rao, Rajeswar Vedula [1 ]
机构：
[1] Natl Inst Technol, Dept Chem, Warangal 506004, Andhra Pradesh, India
来源：
JOURNAL OF CHEMICAL RESEARCH | 2010年 / 01期
关键词：
3-(2-bromoacetyl)coumarin; potassium thiocyanate; arylamine; 1-aryl thiourea; THIAZOLE; HETEROCYCLES; DERIVATIVES; COUMARINS; OXAZOLE;
D O I：
10.3184/030823410X12627991159610
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An efficient synthesis of 3-[2-(arylamino)thiazol-4-yl]coumarins in excellent yields are described. Reaction of 3-(2-bromoacetyl)coumarin with potassium thiocyanate and arylamines, in alcohol resulted in the formation of title compounds in one pot. The same compounds were also prepared by grinding these coumarins and arylthiourea together.
引用
收藏
页码：50 / 53
页数：4
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