A new fluorescent sensor for Cd2+ and its application in living cells imaging

被引：12
|
作者：
Liu, Xiao-yan [1 ]
Liu, Da-ying [1 ]
Qi, Jing [1 ]
Cui, Zhi-gang [2 ]
Chang, He-xi [2 ]
He, Hua-rui [2 ]
Yang, Guang-ming [1 ]
机构：
[1] Nankai Univ, Dept Chem, Tianjin 300071, Peoples R China
[2] Heowns Biochem Technol LLC, Tianjin, Peoples R China
来源：
TETRAHEDRON LETTERS | 2015年 / 56卷 / 11期
基金：
中国国家自然科学基金;
关键词：
Fluorescence sensor; Ionophore; Cadmium; Cell imaging; AQUEOUS-SOLUTION; CADMIUM; CHEMOSENSOR; MERCURY; PROBE; ZN2+; ZINC; LEAD;
D O I：
10.1016/j.tetlet.2015.02.010
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel, fluorescent sensor based on 2,7-dichlorofluorescein with aromatized diethylene triamine as ionophore was developed. Under physiological pH conditions, the sensor exhibited about 70-fold enhancement in fluorescence emission upon binding with Cd2+. It demonstrates that the sensor can be used to detect Cd2+ in aqueous solution and it was successfully applied to image Cd2+ in living cells. (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1322 / 1327
页数：6
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