Family history of psychiatric disorders and alcohol and substance misuse in patients with bipolar I disorder, substance use disorder, or both

被引：5
|
作者：
Sbrana, Alfredo
Bizzarri, Jacopo V.
Rucci, Paola
Gonnelli, Chiara
Massei, Jacopo G.
Ravani, Laura
Endicott, Jean
Maser, Jack D.
Cassano, Giovanni B.
机构：
[1] Univ Pisa, Dept Psychiat Neurobiol Pharmacol & Biotechnol, I-56127 Pisa, Italy
[2] Azienda Sanitaria Bolzano, Serv Dipendenze, Bolzano, Italy
[3] Univ Pittsburgh, Western Psychiat Inst & Clin, Pittsburgh, PA 15213 USA
[4] Columbia Univ, Dept Psychiat, New York, NY 10027 USA
[5] Univ Calif San Diego, Dept Psychiat, La Jolla, CA 92093 USA
[6] Vet Affairs San Diego Healthcare Syst, San Diego, CA USA
来源：
AMERICAN JOURNAL ON ADDICTIONS | 2007年 / 16卷 / 03期
关键词：
1ST-DEGREE RELATIVES; PANIC DISORDER; ABUSE; COMORBIDITY; PSYCHOPATHOLOGY; COOCCURRENCE; MANIA; DEPENDENCE; SIBLINGS; PROBANDS;
D O I：
10.1080/10550490701375699
中图分类号：
R194 [卫生标准、卫生检查、医药管理];
学科分类号：
摘要：
Family history data were collected on first-degree relatives of 78 patients with bipolar I disorder ( BD) and substance use disorder (SUD), 47 with BD only, and 35 with SUD only. The prevalence of psychiatric disorders was significantly higher in first-degree relatives of patients with BD + SUD (64%) and BD (61%) compared with first-degree relatives of SUD patients (20%). The prevalence of alcohol misuse was significantly higher in first-degree relatives of patients with BD + SUD (23.1%) and SUD alone (28.6%) compared to first-degree relatives of patients with BD (4.3%). Our findings suggest that BD and SUD do not share familial risk factors.
引用
收藏
页码：227 / 231
页数：5
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