Family history of psychiatric disorders and alcohol and substance misuse in patients with bipolar I disorder, substance use disorder, or both

被引：5

作者：

Sbrana, Alfredo

Bizzarri, Jacopo V.

Rucci, Paola

Gonnelli, Chiara

Massei, Jacopo G.

Ravani, Laura

Endicott, Jean

Maser, Jack D.

Cassano, Giovanni B.

机构：

[1] Univ Pisa, Dept Psychiat Neurobiol Pharmacol & Biotechnol, I-56127 Pisa, Italy

[2] Azienda Sanitaria Bolzano, Serv Dipendenze, Bolzano, Italy

[3] Univ Pittsburgh, Western Psychiat Inst & Clin, Pittsburgh, PA 15213 USA

[4] Columbia Univ, Dept Psychiat, New York, NY 10027 USA

[5] Univ Calif San Diego, Dept Psychiat, La Jolla, CA 92093 USA

[6] Vet Affairs San Diego Healthcare Syst, San Diego, CA USA

来源：

AMERICAN JOURNAL ON ADDICTIONS | 2007年 / 16卷 / 03期

关键词：

1ST-DEGREE RELATIVES; PANIC DISORDER; ABUSE; COMORBIDITY; PSYCHOPATHOLOGY; COOCCURRENCE; MANIA; DEPENDENCE; SIBLINGS; PROBANDS;

D O I：

10.1080/10550490701375699

中图分类号：

R194 [卫生标准、卫生检查、医药管理];

学科分类号：

摘要：

Family history data were collected on first-degree relatives of 78 patients with bipolar I disorder ( BD) and substance use disorder (SUD), 47 with BD only, and 35 with SUD only. The prevalence of psychiatric disorders was significantly higher in first-degree relatives of patients with BD + SUD (64%) and BD (61%) compared with first-degree relatives of SUD patients (20%). The prevalence of alcohol misuse was significantly higher in first-degree relatives of patients with BD + SUD (23.1%) and SUD alone (28.6%) compared to first-degree relatives of patients with BD (4.3%). Our findings suggest that BD and SUD do not share familial risk factors.

引用

页码：227 / 231

页数：5

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