Fc-silenced bispecific antibodies targeting PD-L1 and 4-1BB combine checkpoint blockade and T-cell co-stimulation to promote anti-tumor activity

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作者
Muik, Alexander [1 ]
Altintas, Isil [2 ]
Gieseke, Friederike [1 ]
Salcedo, Theodora [2 ]
Burm, Saskia [2 ]
Diken, Mustafa [1 ]
Grunwitz, Christian [1 ]
Schuurhuis, Danita [2 ]
Kreiter, Sebastian [1 ]
Satijn, David [2 ]
Tureci, Ozlem [1 ]
Breij, Esther [2 ]
Sahin, Ugur [1 ]
Jure-Kunkel, Maria [2 ]
机构
[1] BioNTech SE, Mainz, Germany
[2] Genmab, Utrecht, Netherlands
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R73 [肿瘤学];
学科分类号
100214 ;
摘要
P609
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页数:2
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