Thiazole substituted [1,2,3] Triazole: Synthesis and antimicrobial evaluation

被引:0
|
作者
Mahale, Keshao A. [1 ]
Gosavi, Kirankumar S. [2 ]
Gaikwad, Nitin D. [1 ]
Bholay, Avinash D. [3 ]
Patil, Sambhaji, V [1 ,4 ]
机构
[1] KRT Arts BH Commerce & AM Sci Coll, Organ Chem Res Ctr, Dept Chem, Gangapur Rd, Nasik 422002, Maharashtra, India
[2] KVPSs Kisan Arts Commerce & Sci Coll, Dept Chem, Parola 425111, Maharashtra, India
[3] KRT Arts BH Commerce & AM Sci Coll, Post Grad Dept Microbiol, Gangapur Rd, Nasik 422002, Maharashtra, India
[4] MVP Samajs Karmaveer Raosaheb Thorat Arts & Comme, Nasik, Maharashtra, India
来源
INDIAN JOURNAL OF CHEMISTRY | 2022年 / 61卷 / 06期
关键词
Thiazole; Triazole; Antimicrobial; MIC; BIOLOGICAL EVALUATION; DERIVATIVES; POTENT; SERIES; INHIBITORS; BINDING;
D O I
暂无
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Novel hybrid molecules containing thiazole and triazole moieties have been efficiently synthesized and characterized by spectroscopic techniques such as IR, NMR, mass spectrometry and elemental analysis. The synthesized hybrid molecules have been screened for their antimicrobial activity against bacterial as well as fungal strains. The minimum inhibitory concentrations have been determined. The investigation of antimicrobial screening data has revealed the most of the compounds exhibited moderate to good microbial activity.
引用
收藏
页码:640 / 649
页数:10
相关论文
共 50 条
  • [41] Synthesis and antimicrobial activity of benzoxazine/benzothiazine appended 1,2,3-triazole hybrids
    Yadav, Priyanka
    Kaushik, C. P.
    Kumar, Devinder
    Parshad, Mahavir
    Yadav, Archna
    Yadav, Jyoti
    JOURNAL OF MOLECULAR STRUCTURE, 2025, 1321
  • [42] Design and Synthesis of New 1,2,3-Triazole-pyrazole Hybrids as Antimicrobial Agents
    Pervaram, S.
    Ashok, D.
    Rao, B. A.
    Sarasija, M.
    Reddy, C. V. R.
    RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2017, 87 (10) : 2454 - 2461
  • [43] Synthesis and Antimicrobial and Antioxidant Activities of 1,2,3-Triazole-Tethered Xanthone Derivatives
    M. Gampa
    P. Padmaja
    S. I. Khalivulla
    P. Narayana Reddy
    Russian Journal of Organic Chemistry, 2022, 58 : 872 - 877
  • [44] Synthesis and Antimicrobial and Antioxidant Activities of 1,2,3-Triazole-Tethered Xanthone Derivatives
    Gampa, M.
    Padmaja, P.
    Khalivulla, S., I
    Reddy, P. Narayana
    RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2022, 58 (06) : 872 - 877
  • [45] Synthesis, Antimicrobial Evaluation, and Docking Studies of Substituted New Chromone Linked 1,2,3-Triazoles
    Nipate, Amol S.
    Jadhav, Chetan K.
    Chate, Asha V.
    Dofe, Vidya S.
    Dixit, Prashant P.
    Sharma, Prachi
    Gill, Charansingh. H.
    POLYCYCLIC AROMATIC COMPOUNDS, 2024, 44 (06) : 3927 - 3944
  • [46] 1,2,3-TRIAZOLE-SUBSTITUTED OLEANOLIC ACID DERIVATIVES: SYNTHESIS AND ANTIPROLIFERATIVE ACTIVITY
    Walter Pertino, Mariano
    Lopez, Cecilia
    Theoduloz, Cristina
    Schmeda-Hirschmann, Guillermo
    PHARMACEUTICAL BIOLOGY, 2012, 50 (05) : 574 - 574
  • [47] A simple and facile synthesis of novel 1,2,3-triazole substituted pyrimidine derivatives
    Bakkolla, Mahesh Goud
    Taduri, Ashok Kumar
    Bhoomireddy, Rama Devi
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2020, 57 (06) : 2489 - 2497
  • [48] A New Method for the Synthesis of Alkyl-Substituted 1,2,3-Triazole Compounds
    Xie, Mingsheng
    Tang, Haoxin
    Zhang, Yiming
    Guo, Zhen
    Guo, Haiming
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2015, 35 (12) : 2589 - 2594
  • [49] 1,2,3-Triazole-Substituted Oleanolic Acid Derivatives: Synthesis and Antiproliferative Activity
    Walter Pertino, Mariano
    Lopez, Cecilia
    Theoduloz, Cristina
    Schmeda-Hirschmann, Guillermo
    MOLECULES, 2013, 18 (07): : 7661 - 7674
  • [50] 1,2,3-triazole-N-oxides .2. Synthesis of substituted 4(5)-ethoxycarbonyl-1,2,3-triazole-N-oxides
    Kirillova, LP
    Shulgina, VM
    Shafeev, MA
    Almukhamedov, AA
    Vereshchagin, LI
    ZHURNAL ORGANICHESKOI KHIMII, 1996, 32 (07): : 1089 - 1092