Thiazole substituted [1,2,3] Triazole: Synthesis and antimicrobial evaluation

被引:0
|
作者
Mahale, Keshao A. [1 ]
Gosavi, Kirankumar S. [2 ]
Gaikwad, Nitin D. [1 ]
Bholay, Avinash D. [3 ]
Patil, Sambhaji, V [1 ,4 ]
机构
[1] KRT Arts BH Commerce & AM Sci Coll, Organ Chem Res Ctr, Dept Chem, Gangapur Rd, Nasik 422002, Maharashtra, India
[2] KVPSs Kisan Arts Commerce & Sci Coll, Dept Chem, Parola 425111, Maharashtra, India
[3] KRT Arts BH Commerce & AM Sci Coll, Post Grad Dept Microbiol, Gangapur Rd, Nasik 422002, Maharashtra, India
[4] MVP Samajs Karmaveer Raosaheb Thorat Arts & Comme, Nasik, Maharashtra, India
来源
INDIAN JOURNAL OF CHEMISTRY | 2022年 / 61卷 / 06期
关键词
Thiazole; Triazole; Antimicrobial; MIC; BIOLOGICAL EVALUATION; DERIVATIVES; POTENT; SERIES; INHIBITORS; BINDING;
D O I
暂无
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Novel hybrid molecules containing thiazole and triazole moieties have been efficiently synthesized and characterized by spectroscopic techniques such as IR, NMR, mass spectrometry and elemental analysis. The synthesized hybrid molecules have been screened for their antimicrobial activity against bacterial as well as fungal strains. The minimum inhibitory concentrations have been determined. The investigation of antimicrobial screening data has revealed the most of the compounds exhibited moderate to good microbial activity.
引用
收藏
页码:640 / 649
页数:10
相关论文
共 50 条
  • [31] Synthesis, antimicrobial evaluation, and in silico studies of quinoline-1H-1,2,3-triazole molecular hybrids
    Awolade, Paul
    Cele, Nosipho
    Kerru, Nagaraju
    Singh, Parvesh
    MOLECULAR DIVERSITY, 2021, 25 (04) : 2201 - 2218
  • [32] Synthesis, antimicrobial evaluation, and in silico studies of quinoline—1H-1,2,3-triazole molecular hybrids
    Paul Awolade
    Nosipho Cele
    Nagaraju Kerru
    Parvesh Singh
    Molecular Diversity, 2021, 25 : 2201 - 2218
  • [33] Synthesis and antifungal potential of 1,2,3-triazole and 1,2,4-triazole thiol substituted strobilurin derivatives
    Chaudhary, Preeti M.
    Tupe, Santosh G.
    Jorwekar, Shweta U.
    Sant, Duhita G.
    Deshpande, Sunita R.
    Maybhate, Shailaja P.
    Likhite, Anjali P.
    Deshpande, Mukund V.
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2015, 54 (07): : 908 - 917
  • [34] 3-SUBSTITUTED 1,2,3-TRIAZOLE-1-OXIDES - PREPARATION AND REACTIONS
    BEGTRUP, M
    JONSSON, G
    ACTA CHEMICA SCANDINAVICA SERIES B-ORGANIC CHEMISTRY AND BIOCHEMISTRY, 1987, 41 (10): : 724 - 735
  • [35] Synthesis of Some New 1,3,4-Thiadiazole, Thiazole and Pyridine Derivatives Containing 1,2,3-Triazole Moiety
    Abdelriheem, Nadia A.
    Mohamed, Ali M. M.
    Abdelhamid, Abdou O.
    MOLECULES, 2017, 22 (02)
  • [36] Synthesis and Biological Activities of Novel Thiophosphoryl Oximates Containing Thiazole and 1,2,3-Triazole Rings
    Zhu Xiaofei
    Shi Deqing
    CHINESE JOURNAL OF CHEMISTRY, 2009, 27 (03) : 565 - 568
  • [37] Antimicrobial polymethacrylates based on quaternized 1,3-thiazole and 1,2,3-triazole side-chain groups
    Tejero, Ruben
    Lopez, Daniel
    Lopez-Fabal, Fatima
    Gomez-Garces, Jose L.
    Fernandez-Garcia, Marta
    POLYMER CHEMISTRY, 2015, 6 (18) : 3449 - 3459
  • [38] SYNTHESIS AND EVALUATION OF CHALCONES CARRYING 1,2,3 TRIAZOLE MOIETY FOR ANTIBACTERIAL AND ANTIOXIDANT ACTIVITY
    Rajeena, Aminath C. H.
    Nayak, Suresh P.
    Ganesh, G.
    Kamat, Vinuta
    Revanasiddappa, B. C.
    Kumar, Hemanth
    HETEROCYCLIC LETTERS, 2018, 8 (01): : 49 - 59
  • [39] Design and synthesis of new 1,2,3-triazole-pyrazole hybrids as antimicrobial agents
    S. Pervaram
    D. Ashok
    B. A. Rao
    M. Sarasija
    C. V. R. Reddy
    Russian Journal of General Chemistry, 2017, 87 : 2454 - 2461
  • [40] Synthesis and Antitumor Activity of 1-Substituted 1,2,3-Triazole-Mollugin Derivatives
    Luo, Han
    Lv, Yong-Feng
    Zhang, Hong
    Hu, Jiang-Miao
    Li, Hong-Mei
    Liu, Shou-Jin
    MOLECULES, 2021, 26 (11):