Microtubule-Tau Interaction as a Therapeutic Target for Alzheimer's Disease

被引：11
|
作者：
Pachima, Yanina Ivashko [1 ,2 ]
Zhou, Liu-yao [3 ,4 ]
Lei, Peng [3 ,4 ,5 ]
Gozes, Illana [1 ,2 ]
机构：
[1] Tel Aviv Univ, Lily & Avraham Gildor Chair Invest Growth Factors, Dept Human Mol Genet & Biochem,Adams Super Ctr Br, Elton Lab Neuroendocrinol,Sackler Fac Med, IL-69978 Tel Aviv, Israel
[2] Tel Aviv Univ, Sagol Sch Neurosci, IL-69978 Tel Aviv, Israel
[3] Sichuan Univ, West China Hosp, State Key Lab Biotherapy, Dept Neurol, Chengdu 610041, Sichuan, Peoples R China
[4] Collaborat Innovat Ctr Biotherapy, Chengdu 610041, Sichuan, Peoples R China
[5] Univ Melbourne, Florey Inst Neurosci & Mental Hlth, Oxidat Biol Unit, Parkville, Vic 3052, Australia
来源：
JOURNAL OF MOLECULAR NEUROSCIENCE | 2016年 / 58卷 / 02期
基金：
中国国家自然科学基金; 以色列科学基金会;
关键词：
DEPENDENT NEUROPROTECTIVE PROTEIN; AMYLOID-BETA-PROTEIN; PAIRED HELICAL FILAMENT; SIGNAL-REGULATED KINASE; FAST AXONAL-TRANSPORT; NAP DAVUNETIDE; MOUSE MODEL; NEURONAL DIFFERENTIATION; ENDOGENOUS TAU; DRUG CANDIDATE;
D O I：
10.1007/s12031-016-0715-x
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：145 / 152
页数：8
相关论文
共 50 条
  • [31] Creatine as a Therapeutic Target in Alzheimer's Disease
    Smith, Aaron N.
    Morris, Jill K.
    Carbuhn, Aaron F.
    Herda, Trent J.
    Keller, Jessica E.
    Sullivan, Debra K.
    Taylor, Matthew K.
    CURRENT DEVELOPMENTS IN NUTRITION, 2023, 7 (11):
  • [32] β-Secretase as a therapeutic target for Alzheimer’s disease
    Arun K. Ghosh
    Sandra Gemma
    Jordan Tang
    Neurotherapeutics, 2008, 5 : 399 - 408
  • [33] β-secretase as a therapeutic target for Alzheimer's disease
    Ghosh, Arun K.
    Gemma, Sandra
    Tang, Jordan
    NEUROTHERAPEUTICS, 2008, 5 (03) : 399 - 408
  • [34] Modulating the microtubule-tau interactions in biomotility systems by altering the chemical environment
    Bhattacharyya, S.
    Kim, K.
    Nakazawa, H.
    Umetsu, M.
    Teizer, W.
    Integrative Biology, 2016, 8 (12) : 1296 - 1300
  • [35] Glycosylation of microtubule-associated protein tau in Alzheimer’s disease brain
    M. Takahashi
    Yasumi Tsujioka
    Tatsuo Yamada
    Yoshio Tsuboi
    Hidechika Okada
    Takayuki Yamamoto
    Zsolt Liposits
    Acta Neuropathologica, 1999, 97 : 635 - 641
  • [36] Glycosylation of microtubule-associated protein tau in Alzheimer's disease brain
    Takahashi, M
    Tsujioka, Y
    Yamada, T
    Tsuboi, Y
    Okada, H
    Yamamoto, T
    Liposits, Z
    ACTA NEUROPATHOLOGICA, 1999, 97 (06) : 635 - 641
  • [37] Role of microtubule-associated protein tau phosphorylation in Alzheimer’s disease
    Rong-hong Ma
    Yao Zhang
    Xiao-yue Hong
    Jun-fei Zhang
    Jian-Zhi Wang
    Gong-ping Liu
    Journal of Huazhong University of Science and Technology [Medical Sciences], 2017, 37 : 307 - 312
  • [38] Role of Microtubule-associated Protein Tau Phosphorylation in Alzheimer's Disease
    马荣红
    张瑶
    洪小月
    张俊菲
    王建枝
    刘恭平
    Current Medical Science, 2017, 37 (03) : 307 - 312
  • [39] Role of microtubule-associated protein tau phosphorylation in Alzheimer's disease
    Ma, Rong-hong
    Zhang, Yao
    Hong, Xiao-yue
    Zhang, Jun-fei
    Wang, Jian-zhi
    Liu, Gong-ping
    JOURNAL OF HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY-MEDICAL SCIENCES, 2017, 37 (03) : 307 - 312
  • [40] CSF tau microtubule binding region identifies tau tangle and clinical stages of Alzheimer's disease
    Horie, Kanta
    Barthelemy, Nicolas R.
    Sato, Chihiro
    Bateman, Randall J.
    BRAIN, 2021, 144 : 515 - 527
12345