Synthesis of isagarin, a tetracyclic naphthoquinone via a palladium-catalyzed cyclization

被引：8
|
作者：
Ploysuk, Chatchawan [1 ]
Kongkathip, Boonsong [1 ]
Kongkathip, Ngampong [1 ]
机构：
[1] Kasetsart Univ, Fac Sci, Natl Prod & Organ Synth Res Unit, Dept Chem, Bangkok 10900, Thailand
来源：
SYNTHETIC COMMUNICATIONS | 2007年 / 37卷 / 7-9期
关键词：
isagarin; naphthoquinone; palladium; synthesis; wacker;
D O I：
10.1080/00397910701227432
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Total synthesis of isagarin (2) has been accomplished in five steps with 24.1% overall yield from 2-bromonaphthoquinone (6). The key step is a palladium-catalyzed cyclization to form a bicyclic ketal ring.
引用
收藏
页码：1463 / 1471
页数：9
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