PHENOLIC CONTENT, ANTI-OXIDATIVE, ANTI-α-AMYLASE AND ANTI-α-GLUCOSIDASE ACTIVITIES OF SOLANUM DIPHYLLUM L.

Total phenolic content, anti-oxidative, anti-alpha-amylase and anti-a-glucosidase activities in the powder extracts of fruits, leaves, roots and stems of Solanum diphyllum were determined. Leaf extract had the highest total polyphenol content (68.1 mg GAE/g), followed by steins (48.6 trip GAE/g), fruits (38 mg GAE/g) and roots (26 mg GAE/g). By employing different assays Such as DPPH radical scavenging, reducing power, Fe(2+) chelating and total anti-oxidant capacity, it was found that leaf and stein extracts had promising anti-oxidative activity. Stem extract had highest level of a-amylase and alpha-glucosidase inhibition at concentrations of 1.0 and 0.5 mg/ml, respectively.