Chemoenzymatic synthesis of 2-brorno-6-hydroxy-3-methoxy-2-cyclohexen-1-one

被引：0

作者：

Karaaslan, Emine Ozgul ^{[1
]}

Toka, Yasemin ^{[1
]}

机构：

[1] Kirikkale Univ, Fac Arts & Sci, Dept Chem, TR-71400 Kirikkale, Turkey

来源：

TURKISH JOURNAL OF CHEMISTRY | 2007年 / 31卷 / 02期

关键词：

chemoenzymatic synthesis; cyclic polyoxo cyclohexenones; manganese (III) acetate; acetoxylation;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A chemoenzymatic synthesis of 2-bromo-6-hydroxy-3-methoxy-2-cyclohexen-1-one starting from cyclohexane-1,3-dione is reported. Manganese (III) acetate-mediated acetoxylation followed by the enzyme-mediated hydrolysis of alpha'-acetoxy enone affords hydroxy-enone 5 and enone 4 with high enantiomeric excesses in good yields.

引用

页码：149 / 153

页数：5

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