Chemoenzymatic synthesis of 2-brorno-6-hydroxy-3-methoxy-2-cyclohexen-1-one

被引：0

作者：

Karaaslan, Emine Ozgul ^{[1
]}

Toka, Yasemin ^{[1
]}

机构：

[1] Kirikkale Univ, Fac Arts & Sci, Dept Chem, TR-71400 Kirikkale, Turkey

来源：

TURKISH JOURNAL OF CHEMISTRY | 2007年 / 31卷 / 02期

关键词：

chemoenzymatic synthesis; cyclic polyoxo cyclohexenones; manganese (III) acetate; acetoxylation;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A chemoenzymatic synthesis of 2-bromo-6-hydroxy-3-methoxy-2-cyclohexen-1-one starting from cyclohexane-1,3-dione is reported. Manganese (III) acetate-mediated acetoxylation followed by the enzyme-mediated hydrolysis of alpha'-acetoxy enone affords hydroxy-enone 5 and enone 4 with high enantiomeric excesses in good yields.

引用

页码：149 / 153

页数：5

共 50 条

[21] 6-(1-hydroxy-2,2-diphenylethyl)-4,4-diphenyl-2-cyclohexen-1-one
Kumar, VSS
Nangia, A
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, 2000, 56 : 360 - 361
[22] 6-(1-Hydroxy-2,2-diphenylethyl)-4,4-diphenyl-2-cyclohexen-1-one
Kumar, V.S. Senthil
Nangia, Ashwini
Acta Crystallographica, Section C: Crystal Structure Communications, 2000, 56 (03) : 360 - 361
[23] PREPARATION OF 3-(6-METHOXYNAPHTHYL-2)-2-CYCLOHEXEN-1-ONE AND RELATED COMPOUNDS
NOVELLO, FC
CHRISTY, ME
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1953, 75 (21) : 5431 - 5432
[24] 2,2′-[(3-hydroxyphenyl)methylene]bis(3-hydroxy-5,5-dimethyl-2-cyclohexen-1-one) hydrate
Bolte, M
Degen, A
Rühl, S
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2001, 57 : O170 - o171
[25] SYNTHESIS AND INVESTIGATION OF SULPHONATION OF 6-METHOXY-2-PHENYL-3-HYDROXYPYRIDINES AND 6-HYDROXY-2-PHENYL-3-HYDROXYPYRIDINES
SMIRNOV, LD
AVEZOV, MR
LEZINA, VP
ALIEVA, RO
DYUMAEV, RM
IZVESTIYA AKADEMII NAUK SSSR-SERIYA KHIMICHESKAYA, 1971, (03): : 623 - &
[26] 2-METHOXY-5-(1,2,3,4-TETRAHYDRO-7-HYDROXY-6-METHOXY-2-METHYLISOQUINOL-1-YLMETHYL)PHENYL-4-(1,2,3,4-TETRAHYDRO-6-HYDROXY-7-METHOXY-2-METHYLISOQUINOL-1-YLMETHYL)PHENYL-ETHER
COUTTS, IGC
DURBIN, AK
SCHOFIEL.K
AUSTRALIAN JOURNAL OF CHEMISTRY, 1970, 23 (04) : 791 - &
[27] AN IMPROVED SYNTHESIS OF 4-METHYLENE-2-CYCLOHEXEN-1-ONE
JUNG, ME
RAYLE, HL
SYNTHETIC COMMUNICATIONS, 1994, 24 (02) : 197 - 203
[28] NOTE ON THE SYNTHESIS OF 6-HYDROXY-2-ISOPROPYL-5-METHOXY-3(2H)-BENZOFURANONE
BOHLMANN, F
VORWERK, E
CHEMISCHE BERICHTE-RECUEIL, 1979, 112 (03): : 1074 - 1075
[29] SYNTHESIS OF ISOMERIC 6-ACETYL-3,5-DIARYL-2-CYCLOHEXEN-1-ONES AND 3-CYCLOHEXEN-1-ONES
BAPAT, UR
MANJREKAR, PP
HOSANGADI, BD
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1989, 28 (10): : 810 - 813
[30] ACYLATIONS OF 6-HYDROXY-2-ISOPROPYLBENZOFURAN AND 6-METHOXY-2-ISOPROPYLBENZOFURAN AND SYNTHESIS OF FUROCHROMENONES
YAMAGUCHI, S
KAWASE, Y
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1979, (APR): : 48 - 48

← 1 2 3 4 5 →