Taking thalidomide out of rehab

被引：13

作者：

Akhurst, Rosemary J. ^{[1
,2
]}

机构：

[1] Univ Calif San Francisco, Helen Diller Family Comprehens Canc Ctr, San Francisco, CA 94143 USA

[2] Univ Calif San Francisco, Dept Anat, San Francisco, CA 94143 USA

来源：

NATURE MEDICINE | 2010年 / 16卷 / 04期

关键词：

HEREDITARY HEMORRHAGIC TELANGIECTASIA; GROWTH-FACTOR-BETA; ANGIOGENESIS; MICE; BEVACIZUMAB; DEFECTS; VEGF;

D O I：

10.1038/nm0410-370

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Thalidomide, a drug reviled in the 1960s for its teratogenic effects, has been revived in recent years for cancer and leprosy therapy. A study now finds another use for this drug in vascular disease, providing further insights into the drug's mechanisms of action (pages 420-428).

引用

页码：370 / 372

页数：4

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