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Taking thalidomide out of rehab
被引:13
|作者:
Akhurst, Rosemary J.
[1
,2
]
机构:
[1] Univ Calif San Francisco, Helen Diller Family Comprehens Canc Ctr, San Francisco, CA 94143 USA
[2] Univ Calif San Francisco, Dept Anat, San Francisco, CA 94143 USA
关键词:
HEREDITARY HEMORRHAGIC TELANGIECTASIA;
GROWTH-FACTOR-BETA;
ANGIOGENESIS;
MICE;
BEVACIZUMAB;
DEFECTS;
VEGF;
D O I:
10.1038/nm0410-370
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
Thalidomide, a drug reviled in the 1960s for its teratogenic effects, has been revived in recent years for cancer and leprosy therapy. A study now finds another use for this drug in vascular disease, providing further insights into the drug's mechanisms of action (pages 420-428).
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页码:370 / 372
页数:4
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