Taking thalidomide out of rehab

被引：13
|
作者：
Akhurst, Rosemary J. [1 ,2 ]
机构：
[1] Univ Calif San Francisco, Helen Diller Family Comprehens Canc Ctr, San Francisco, CA 94143 USA
[2] Univ Calif San Francisco, Dept Anat, San Francisco, CA 94143 USA
来源：
NATURE MEDICINE | 2010年 / 16卷 / 04期
关键词：
HEREDITARY HEMORRHAGIC TELANGIECTASIA; GROWTH-FACTOR-BETA; ANGIOGENESIS; MICE; BEVACIZUMAB; DEFECTS; VEGF;
D O I：
10.1038/nm0410-370
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Thalidomide, a drug reviled in the 1960s for its teratogenic effects, has been revived in recent years for cancer and leprosy therapy. A study now finds another use for this drug in vascular disease, providing further insights into the drug's mechanisms of action (pages 420-428).
引用
收藏
页码：370 / 372
页数：4
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