First total synthesis of (+)-Carainterol A

被引:23
|
作者
Ma, Kaiqing [1 ]
Zhang, Chunbo [2 ]
Liu, Mingming [1 ]
Chu, Yong [1 ]
Zhou, Lu [1 ]
Hu, Changqi [1 ]
Ye, Deyong [1 ]
机构
[1] Fudan Univ, Sch Pharm, Dept Med Chem, Shanghai 201203, Peoples R China
[2] Yanbian Univ, Minist Educ, Key Lab Nat Resources & Funct Mol Changbai Mt, Yanji 133000, Jilin, Peoples R China
基金
美国国家科学基金会;
关键词
CARBONYL-COMPOUNDS; ENANTIOSELECTIVE SYNTHESIS; GRIGNARD-REAGENTS; SESQUITERPENOIDS; EUDESMANE; ALCOHOLS; KETONES;
D O I
10.1016/j.tetlet.2010.02.001
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The first, stereospecific, and elegant synthesis of the natural product (+)-Carainterol A was developed by using the Robinson annulation reaction as a key step to build the eudesmane skeleton. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1870 / 1872
页数:3
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